Shanghai Jiao Tong University, School of Nursing, Shanghai, China.
Department of Nephrology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Int Urol Nephrol. 2021 May;53(5):1033-1042. doi: 10.1007/s11255-020-02737-y. Epub 2021 Jan 3.
Identifying performance-based tests that meaningful for patients may facilitate the implementation of rehabilitation programs. The primary aim of this study was to determine the independent associations between different performance-based tests and health-related quality of life (HRQoL) among elderly peritoneal dialysis (PD) patients.
This cross-sectional study was conducted in China. Patients on PD who were 60 years of age or above were included. HRQoL was assessed using the Medical Outcomes Study Short Form 36. Physical function was determined by handgrip strength, timed up and go (TUG) test, 5-repetition sit-to-stand test, and comfortable gait speed. Depressive symptoms were measured using the self-reported Geriatric Depression Scale (GDS-15). Multiple linear regression analyses were performed to examine the factors influencing HRQoL.
In total, 115 participants with a mean age of 69.7 were included (46 women and 69 men). TUG (β =- 0.460, p < 0.001), prealbumin (β = 0.223, p = 0.014), and education level (β = 0.183, p = 0.042) were associated with physical health. GDS score (β = - 0.475, p < 0.001), serum albumin level (β = 0.264, p = 0.003), and sex (β = 0.217, p = 0.012), were associated with mental HRQoL.
TUG could be a valuable test for use in clinical practice and research aiming at facilitating tailed exercise programs, as it was associated with self-perceived physical HRQoL and could be meaningful to elderly PD patients. Depressive symptoms and nutrition were another two important rehabilitation areas for optimizing the overall HRQoL of older adults on PD.
确定对患者有意义的基于表现的测试可能有助于康复计划的实施。本研究的主要目的是确定不同基于表现的测试与老年腹膜透析（PD）患者健康相关生活质量（HRQoL）之间的独立关联。
这是一项在中国进行的横断面研究。纳入年龄在 60 岁及以上的 PD 患者。使用医疗结局研究短表 36 评估 HRQoL。身体功能通过握力、计时起立行走测试（TUG）、5 次重复坐立站起测试和舒适步行速度来确定。抑郁症状采用自评老年抑郁量表（GDS-15）进行测量。采用多元线性回归分析来检验影响 HRQoL 的因素。
共纳入 115 名参与者，平均年龄为 69.7 岁（46 名女性，69 名男性）。TUG（β=-0.460，p<0.001）、前白蛋白（β=0.223，p=0.014）和教育程度（β=0.183，p=0.042）与身体健康相关。GDS 评分（β=-0.475，p<0.001）、血清白蛋白水平（β=0.264，p=0.003）和性别（β=0.217，p=0.012）与心理健康 HRQoL 相关。
TUG 可能是一种在临床实践和研究中很有价值的测试，因为它与自我感知的身体 HRQoL 相关，并且对老年 PD 患者可能有意义。抑郁症状和营养是优化老年 PD 患者整体 HRQoL 的另外两个重要康复领域。
