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利用非激光和激光工具为老年患者进行安全有效的经静脉导线拔除:日本单中心经验。

Safe and effective transvenous lead extraction for elderly patients utilizing non-laser and laser tools: a single-center experience in Japan.

机构信息

Department of Cardiovascular Medicine, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, Nagano, 390-8621, Japan.

Department of Cardiology, Tokyo Women's Medical University, Tokyo, Japan.

出版信息

Heart Vessels. 2021 Jun;36(6):882-889. doi: 10.1007/s00380-020-01761-3. Epub 2021 Jan 4.

Abstract

Transvenous lead extraction (TLE) for cardiac implantable electric device (CIED) infection is becoming increasingly common, but is believed to be particularly risky in elderly patients. This study aimed to clarify the safety and effectiveness of TLE in the elderly, evaluating the use of both non-laser and laser extraction tools. We retrospectively analyzed the characteristics, device type, indications, procedures, and clinical results in younger (YG; age: 15-79 years; n = 48) and elderly groups (EG; age: ≥ 80 years; n = 27) of patients who underwent percutaneous TLE between April 2014 and December 2019 at our hospital. The average age was 68 and 88 years in the YG and EG, respectively. Indications for TLE were infection in 33 (68.8%) patients and other in 15 (30.6%) patients in the YG, and infection in all 27 (100%) EG patients. Bloodstream infection was detected in 9 and 4 patients in the YG and EG, respectively, with methicillin-resistant Staphylococcus epidermidis being the most common causative pathogen. All TLE procedures were performed under general anesthesia in an operating room with cardiovascular surgeon backup. An excimer laser sheath (76 leads), a laser followed by a mechanical sheath (45 leads), Evolution RL (17 leads), a mechanical sheath (9 leads), and manual traction (one lead) were employed to extract a total of 148 leads (98 and 50 in the YG and EG, respectively). A mechanical sheath or Evolution RL was more frequently used in the YG. The respective average implantation durations in the YG and EG were 5.3 and 5.0 years, respectively, which were comparable (p = 0.46). Procedural success rates were identical between the YG and EG (99% vs. 100%, respectively). There was only one procedure-related complication in the entire cohort (cardiac tamponade in a YG patient). Taken together, the success rates of TLE were high in the EG, with no complications, with extraction being the indication for infection in all EG patients. Percutaneous TLE was safe and effective in elderly patients using both non-laser and laser techniques.

摘要

经静脉心脏植入式电子装置(CIED)感染的导线拔除(TLE)越来越常见,但据信在老年患者中风险特别高。本研究旨在明确 TLE 在老年人中的安全性和有效性,评估使用非激光和激光提取工具的效果。我们回顾性分析了 2014 年 4 月至 2019 年 12 月在我院接受经皮 TLE 的年轻组(年龄:15-79 岁;n=48)和老年组(年龄:≥80 岁;n=27)患者的特征、装置类型、适应证、程序和临床结果。年轻组和老年组的平均年龄分别为 68 岁和 88 岁。TLE 的适应证为年轻组感染 33 例(68.8%),其他 15 例(30.6%),老年组所有 27 例(100%)均为感染。年轻组和老年组分别有 9 例和 4 例患者检测到血流感染,最常见的病原体是耐甲氧西林表皮葡萄球菌。所有 TLE 程序均在手术室全身麻醉下进行,由心血管外科医生支持。共拔除 148 根导线(年轻组 98 根,老年组 50 根),使用了准分子激光鞘(76 根)、激光加机械鞘(45 根)、Evolution RL(17 根)、机械鞘(9 根)和手动牵引(1 根)。年轻组和老年组分别有 17 例和 10 例患者植入了 CIED,平均植入时间分别为 5.3 年和 5.0 年,差异无统计学意义(P=0.46)。两组患者的手术成功率相同(分别为 99%和 100%)。整个队列中只有 1 例手术相关并发症(年轻组患者发生心脏压塞)。综上所述,老年患者 TLE 成功率高,无并发症,所有老年患者的拔除指征均为感染。使用非激光和激光技术,经皮 TLE 对老年患者安全有效。

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