Khanna Raoul Kanav, Pichard Tiphanie, Pasco Jeremy, Dorvault Marta, Cook Ann-Rose, Pisella Pierre-Jean, Arsene Sophie
Department of Ophthalmology, Bretonneau University Hospital, 2 boulevard Tonnellé, 37044, Tours, France.
Neurogénétique et Physiopathologie neuronale, iBrain, INSERM, U1253, University of Tours, Tours, France.
Graefes Arch Clin Exp Ophthalmol. 2021 Jul;259(7):1723-1730. doi: 10.1007/s00417-020-05064-1. Epub 2021 Jan 4.
Binocular visual impairment related to unilateral idiopathic epiretinal membranes (uiERM) and its association with vision-related quality of life (VR-QoL) has not yet been investigated. This study aimed to explore binocular visual parameters (distance binocular best-corrected visual acuity (BCVA), aniseikonia, stereopsis) and VR-QoL in patients with uiERM.
We carried out a prospective single-centre cohort study. The following data were collected: VR-QoL (NEI VFQ-25), distance monocular and binocular BCVA, horizontal and vertical metamorphopsia (M-charts test), horizontal and vertical aniseikonia (NAT TEST) and stereoacuity (TNO test). Multiple linear regression analyses were performed to evaluate factors influencing VR-QoL.
Forty-six patients with uiERM and visual complaints were included. Aniseikonia was found in 40 (80%) participants. Stereoacuity was poor (above 120 s of arc) in 46 (100%) participants. Distance monocular BCVA, horizontal metamorphopsia and horizontal aniseikonia were the factors associated with VR-QoL in patients with uiERM.
In subjects presenting uiERM, aniseikonia is frequently found and stereopsis is constantly impaired. We advocate quantitative testing of metamorphopsia and aniseikonia in addition to BCVA for the assessment of global visual function. Further investigations are needed to evaluate the effect of vitrectomy on these parameters and VR-QoL.
EudraCT Number/ID RCB: 2016-A00252-49.
与单侧特发性视网膜前膜（uiERM）相关的双眼视力损害及其与视力相关生活质量（VR-QoL）的关联尚未得到研究。本研究旨在探讨uiERM患者的双眼视觉参数（远距离双眼最佳矫正视力（BCVA）、不等像、立体视）和VR-QoL。
我们开展了一项前瞻性单中心队列研究。收集了以下数据：VR-QoL（NEI VFQ-25）、远距离单眼和双眼BCVA、水平和垂直变视症（M-图表测试）、水平和垂直不等像（NAT测试）以及立体视锐度（TNO测试）。进行多元线性回归分析以评估影响VR-QoL的因素。
纳入了46例有视力问题的uiERM患者。40例（80%）参与者存在不等像。46例（100%）参与者的立体视锐度较差（超过120角秒）。远距离单眼BCVA、水平变视症和水平不等像是与uiERM患者VR-QoL相关的因素。
在出现uiERM的受试者中，经常发现不等像且立体视持续受损。除了BCVA外，我们主张对变视症和不等像进行定量测试以评估整体视觉功能。需要进一步研究来评估玻璃体切除术对这些参数和VR-QoL的影响。
EudraCT编号/ID RCB：2016-A00252-49。
