Drewry M M, Harris R B, Martin R J
Department of Foods and Nutrition, College of Home Economics, University of Georgia, Athens 30602.
J Nutr. 1988 Feb;118(2):194-8. doi: 10.1093/jn/118.2.194.
It has been proposed that voluntary food intake limits growth rate. The experiment described here investigated the effects of increased food intake on growth rate. Four age groups of female rats were given either 150 or 100 of ad libitum intake by oral gavage. Animals were tube-fed at these levels of intake for 1 wk. Overfeeding significantly increased carcass weight and fat for all ages examined. Carcass protein was significantly elevated in the overfed animals for the two youngest age groups. Differences between age groups in apparent energetic efficiency were small. Hepatic palmitate oxidation was depressed and esterification increased in all overfed rats. Fat cell size was increased by overfeeding in all age groups. In conclusion, the effects of overfeeding on the four age groups of rats studied were independent of age.
有人提出，自愿限制食物摄入量会影响生长速度。本文所述的实验研究了增加食物摄入量对生长速度的影响。将四个年龄组的雌性大鼠通过灌胃给予自由采食摄入量的150%或100%。动物在这些摄入量水平下管饲1周。对于所有检查的年龄组，过量喂食显著增加了胴体重量和脂肪。在两个最年轻的年龄组中，过量喂食的动物胴体蛋白质显著升高。各年龄组之间的表观能量效率差异很小。所有过量喂食的大鼠肝脏棕榈酸氧化受到抑制，酯化增加。所有年龄组的过量喂食均增加了脂肪细胞大小。总之，过量喂食对所研究的四个年龄组大鼠的影响与年龄无关。
