Department of Anesthesiology, Duke University School of Medicine, Durham, North Carolina, USA.
Curr Opin Crit Care. 2021 Apr 1;27(2):169-176. doi: 10.1097/MCC.0000000000000801.
Existing data and all ICU nutrition guidelines emphasize enteral nutrition (EN) represents a primary therapy leading to both nutritional and non-nutritional benefits. Unfortunately, iatrogenic malnutrition and underfeeding is virtually ubiquitous in ICUs worldwide for prolonged periods post-ICU admission. Overcoming essential challenges to EN delivery requires addressing a range of real, and frequently propagated myths regarding EN delivery.
Key recent data addresses perceived challenges to EN including: Adequately resuscitated patients on vasopressors can and likely should receive trophic early EN and this was recently associated with reduced mortality; Patients paralyzed with neuromuscular blocking agents can and should receive early EN as this was recently associated with reduced mortality/hospital length of stay; Proned patients can safely receive EN; All ICU nutrition delivery, including EN, should be objectively guided by indirect calorimetry (IC) measures. This is now possible with the new availability of a next-generation IC device.
It is the essential implementation of this new evidence occurs to overcome real and perceived EN challenges. This data should lead to increased standardization/protocolization of ICU nutrition therapy to ensure personalized nutrition care delivering the right nutrition dose, in the right patient, at the right time to optimize clinical outcome.
现有数据和所有 ICU 营养指南都强调肠内营养(EN)是主要治疗方法,可带来营养和非营养益处。不幸的是,在 ICU 后入住期间,全世界的 ICU 中几乎普遍存在医源性营养不良和喂养不足。为了克服 EN 输送的基本挑战,需要解决一系列关于 EN 输送的实际问题和经常传播的误解。
最近的关键数据解决了对 EN 的感知挑战,包括:接受血管加压药充分复苏的患者可以并且可能应该接受营养早期 EN,最近这与降低死亡率相关;接受神经肌肉阻滞剂麻痹的患者可以并且应该接受早期 EN,因为最近这与降低死亡率/住院时间相关;俯卧位患者可以安全地接受 EN;所有 ICU 营养输送,包括 EN,都应通过间接热量测定(IC)测量进行客观指导。这现在可以通过新一代 IC 设备的新可用性来实现。
克服实际和感知到的 EN 挑战的关键是必须实施这些新证据。这些数据应导致 ICU 营养治疗的标准化/方案化增加,以确保个性化营养护理,为患者提供正确的营养剂量,在正确的时间,以优化临床结果。