Department of Sensory Organ Studies, Nicolaus Copernicus University, Collegium Medicum, Bydgoszcz, Poland.
Oftalmika Eye Hospital, Bydgoszcz, Poland.
Retina. 2021 Aug 1;41(8):1627-1634. doi: 10.1097/IAE.0000000000003096.
To examine the relationship between retinal sensitivity and the area of internal limiting membrane (ILM) peeling during pars plana vitrectomy for a full-thickness macular hole.
Twenty-four eyes a minimum of 6 months after temporal inverted flap pars plana vitrectomy for a full-thickness macular hole were included in the study. En face spectral-domain optical coherence tomography images were used to assess margins of the peeled ILM area. Microperimetry was performed to examine retinal sensitivity within the central 10°. Areas of peeled ILM in en face optical coherence tomography images were correlated with the average sensitivity threshold. Retinal sensitivities at the location of each measurement point were compared with structural abnormalities observed in en face spectral-domain optical coherence tomography images.
The mean retinal sensitivity in the area of ILM removal was significantly lower compared with the area of preserved ILM (24.29 ± 3.96 dB vs. 26.19 ± 2.10 dB, P < 0.0001, respectively). The peeled ILM area showed a negative correlation with the average sensitivity threshold (r = -0.56, P < 0.01).
A larger area of ILM peeling during temporal inverted flap pars plana vitrectomy for a full-thickness macular hole is related to lower retinal sensitivity in the central macula.
研究全层黄斑裂孔经巩膜平坦部玻璃体切除术中内界膜（ILM）剥除面积与视网膜敏感度的关系。
本研究纳入了 24 只眼，这些眼均在经巩膜平坦部玻璃体切除术后 6 个月以上接受了颞侧反转式内界膜瓣手术治疗。采用频域光学相干断层扫描（SD-OCT）对经巩膜平坦部玻璃体切除术后内界膜剥除范围进行评估。微视野计用于检测黄斑中心 10°范围内的视网膜敏感度。并将 OCT 图像中内界膜剥除面积与平均敏感度阈值进行相关性分析。比较各测量点的视网膜敏感度与频域 OCT 图像中观察到的结构异常。
与保留内界膜的区域相比，ILM 切除区域的平均视网膜敏感度明显降低（24.29 ± 3.96 dB 比 26.19 ± 2.10 dB，P < 0.0001）。ILM 剥除面积与平均敏感度阈值呈负相关（r = -0.56，P < 0.01）。
颞侧反转式内界膜瓣玻璃体切除术治疗全层黄斑裂孔时，ILM 剥除面积越大，黄斑中心的视网膜敏感度越低。
