Gokada Maheswara Rao, Pasupuleti Visweswara Rao, Bollikolla Hari Babu
Department of Chemistry, Acharya Nagarjuna University, N Nagar, Guntur-522510, AP, India.
Department of Biomedical Sciences & Therapeutics, Faculty of Medicine and Health Sciences, University Malaysia Sabah, 88400, Kota Kinabalu Sabah, Malaysia.
Mini Rev Med Chem. 2021;21(10):1173-1181. doi: 10.2174/1389557521666210104165733.
The novel Coronavirus disease (COVID-19) is an epidemic disease that appeared at the end of the year 2019 with a sudden increase in number and came to be considered as a pandemic disease caused by a viral infection which has threatened most countries for an emergency search for new anti-SARS-COV drugs /vaccines. At present, the number of clinical trials is ongoing worldwide on different drugs i.e. Hydroxychloroquine, Remedisvir, Favipiravir that utilize various mechanisms of action. A few countries are currently processing clinical trials, which may result in a positive outcome. Favipiravir (FPV) represents one of the feasible treatment options for COVID-19, if the result of the trials turns out positive. Favipiravir will be one of the developed possibly authoritative drugs to warrant benefits to mankind with large-scale production to meet the demands of the current pandemic Covid-19 outbreak and future epidemic outbreaks. In this review, the authors tried to explore key molecules, which will be supportive for devising COVID-19 research.
