Department of Urology, University College London Hospital, London, United Kingdom; Division of Surgery and Interventional Science, University College London, United Kingdom.
Department of Urology, University College London Hospital, London, United Kingdom; Division of Experimental Oncology/Unit of Urology, URI, IRCCS Ospedale San Raffaele, Milan, Italy.
Urol Oncol. 2021 Mar;39(3):197.e9-197.e17. doi: 10.1016/j.urolonc.2020.12.005. Epub 2021 Jan 1.
To develop an international consensus on managing penile cancer patients during the COVID-19 acute waves. A major concern for patients with penile cancer during the coronavirus disease 2019 (COVID-19) pandemic is how the enforced safety measures will affect their disease management. Delays in diagnosis and treatment initiation may have an impact on the extent of the primary lesion as well as the cancer-specific survival because of the development and progression of inguinal lymph node metastases.
A review of the COVID-19 literature was conducted in conjunction with analysis of current international guidelines on the management of penile cancer. Results were presented to an international panel of experts on penile cancer and infection control by a virtual accelerated Delphi process using 4 survey rounds. Consensus opinion was defined as an agreement of ≥80%, which was used to reconfigure management pathways for penile cancer.
Limited evidence is available for delaying penile cancer management. The consensus rate of agreement was 100% that penile cancer pathways should be reconfigured, and measures should be developed to prevent perioperative nosocomial transmission of COVID-19. The panel also reached a consensus on several statements aimed at reconfiguring the management of penile cancer patients during the COVID-19 pandemic.
The international consensus panel proposed a framework for the diagnostic and invasive therapeutic procedures for penile cancer within a low-risk environment for COVID-19.
在 COVID-19 急性浪潮期间为阴茎癌患者的管理制定国际共识。在 2019 年冠状病毒病（COVID-19）大流行期间，阴茎癌患者的主要关注点是强制性安全措施将如何影响他们的疾病管理。由于腹股沟淋巴结转移的发展和进展，诊断和治疗开始的延迟可能会对原发灶的范围以及癌症特异性生存率产生影响。
对 COVID-19 文献进行了回顾，并结合当前关于阴茎癌管理的国际指南进行了分析。结果通过虚拟加速 Delphi 过程，使用 4 轮调查，向阴茎癌和感染控制方面的国际专家小组进行了介绍。将≥80%的一致性定义为共识意见，用于重新配置阴茎癌的管理途径。
目前关于延迟阴茎癌管理的证据有限。一致同意的比例为 100%，即应重新配置阴茎癌途径，并应制定措施以防止 COVID-19 围手术期医院内传播。专家组还就旨在重新配置 COVID-19 大流行期间阴茎癌患者管理的几项声明达成共识。
国际共识专家组提出了在 COVID-19 低风险环境下进行阴茎癌诊断和侵入性治疗程序的框架。
