Dr Mohammad Abdus Sattar Bhuiyan, Assistant Professor, Department of Cardiology, Mymensingh Medical College (MMC), Mymensingh, Bangladesh; E-mail:
Mymensingh Med J. 2021 Jan;30(1):21-27.
Patients with Diabetes Mellitus are at high risk of cardiovascular events because of abnormal lipid metabolism. Dyslipidemia is common in patients with Diabetes Mellitus (DM). However; in Bangladesh this issue is not yet properly addressed. The aim of this study is to determine the prevalence and patterns of dyslipidaemia in patients with DM in a divisional city Mymensingh. This cross-sectional study was conducted in randomly selected eligible patients from the indoor registry of the Department of Cardiology, Mymensingh Medical College Hospital (MMCH), Bangladesh from April 2012 to March 2013. A well structured questionnaire and blood investigation for lipid profile and blood sugar were the tools of data collection from 120 randomly selected DM patients registered in the department of cardiology, MMCH. Out of 120 enrolled participants the prevalence of dyslipidemia in DM patients was 86.0%, prevalence of dyslipidemia in males was 88.0% while in females was 85.0% but the difference was not significant (p=0.42). Regarding age group, BMI and duration of DM, there is no significant association exists with dyslipidemia. About half of the studied DM patients have high serum total cholesterol level (50.83%), while 22.5% had low serum HDL-C levels and 35.0% had high serum LDC-C level, most of patients had serum triglyceride levels above normal range (67.5%) and so the common patterns of dyslipidemia in this study were serum triglyceride level followed by total cholesterol. High prevalence of dyslipidemia among diabetes mellitus in Mymensingh city were observed and so the common patterns of dyslipidemia is triglyceride followed by total cholesterol. This study emphasizes the importance of screening of lipid profile as these abnormalities may lead to development of cardiovascular diseases.
患有糖尿病的患者由于脂质代谢异常，其心血管事件发生风险较高。血脂异常在糖尿病患者中较为常见。然而，在孟加拉国，这个问题尚未得到妥善解决。本研究旨在确定在孟加拉国迈门辛市的一个分区城市中，糖尿病患者的血脂异常患病率和模式。这是一项横断面研究，于 2012 年 4 月至 2013 年 3 月期间，在孟加拉国迈门辛医学院医院（MMCH）心脏病科的门诊登记处随机选择符合条件的 120 名糖尿病患者进行。使用问卷调查表和血液检查来检测血脂谱和血糖，是从 MMCH 心脏病科登记的 120 名糖尿病患者中收集数据的工具。在 120 名入组参与者中，糖尿病患者血脂异常的患病率为 86.0%，男性患病率为 88.0%，女性患病率为 85.0%，但差异无统计学意义（p=0.42）。关于年龄组、BMI 和糖尿病持续时间，与血脂异常无显著相关性。约一半的研究糖尿病患者有高血清总胆固醇水平（50.83%），22.5%有低血清高密度脂蛋白胆固醇水平，35.0%有高血清低密度脂蛋白胆固醇水平，大多数患者的血清甘油三酯水平高于正常值（67.5%），因此本研究中血脂异常的常见模式是血清甘油三酯水平，其次是总胆固醇。在迈门辛市观察到糖尿病患者血脂异常的高患病率，因此血脂异常的常见模式是甘油三酯，其次是总胆固醇。本研究强调了筛查血脂谱的重要性，因为这些异常可能导致心血管疾病的发生。
