Das Hrishov, Banik Sujan
Department of Pharmacy, Noakhali Science and Technology University, Noakhali, 3814, Bangladesh.
Department of Pharmacy, Noakhali Science and Technology University, Noakhali, 3814, Bangladesh.
Diabetes Metab Syndr. 2019 Jan-Feb;13(1):252-257. doi: 10.1016/j.dsx.2018.09.006. Epub 2018 Sep 8.
Diabetic dyslipidemia is one of the major risk factors for cardiovascular disease which has a vast mortality rate throughout the world. Early detection and treatment of dyslipidemia can avoid risk for cardiovascular disorder in diabetic patients. This study was conducted to determine the prevalence of and pattern of dyslipidemia in diabetic patients.
This cross sectional study was performed in several specialized diabetic hospital of Noakhali, a southern district of Bangladesh. All known cases of diabetes mellitus were evaluated for their lipid profile. A total number of 1008 patients were included in the study having 683 (67.8%) female and 325 (32.2%) male subjects.
The prevalence of dyslipidemia among the male subjects was 73% while among female subjects 71%. Among diabetic males the percentage of high serum Cholesterol, high serum TG (Triglyceride), low HDL (High density cholesterol) and high LDL (Low density cholesterol) was 35.69%, 44.31%, 50.15% and 72.92% respectively, whereas the female had the percentage at 35.29%, 40.85%, 49.49% and 70.57% respectively.
Majority portion of the study subjects were dyslipidemic. The most prevalent pattern among both male and female was high level of LDL and low level of HDL. The prevalence of dyslipidemia in Bangladesh is significantly high, which indicates the urgency of lifestyle intervention strategies to prevent and manage this important health problem and risk factor.
糖尿病血脂异常是心血管疾病的主要危险因素之一，在全球范围内具有很高的死亡率。早期发现和治疗血脂异常可避免糖尿病患者发生心血管疾病的风险。本研究旨在确定糖尿病患者血脂异常的患病率及模式。
本横断面研究在孟加拉国南部诺阿卡利的几家专业糖尿病医院进行。对所有已知糖尿病病例进行血脂谱评估。共有1008例患者纳入研究，其中女性683例（67.8%），男性325例（32.2%）。
男性受试者血脂异常患病率为73%，女性受试者为71%。在糖尿病男性中，高血清胆固醇、高血清甘油三酯（TG）、低高密度脂蛋白（HDL）和高低密度脂蛋白（LDL）的百分比分别为35.69%、44.31%、50.15%和72.92%，而女性的百分比分别为35.29%、40.85%、49.49%和70.57%。
研究对象中大部分存在血脂异常。男性和女性中最常见的模式是LDL水平高和HDL水平低。孟加拉国血脂异常的患病率显著较高，这表明采取生活方式干预策略来预防和管理这一重要健康问题及危险因素的紧迫性。
