Hayashi Y, Kawamoto H, Sasao T, Nagusa Y, Iwamori S
Dept. of Pathology, Hiroshima City Asa Hospital.
Gan No Rinsho. 1988 Jan;34(1):33-40.
Adenomas of the breast are cellular epithelial lesions, which are subclassified into two types, tubular adenomas (TA) and lactating adenomas (LA). In 3365 cases of benign epithelial tumors of the breast, including fibroadenomas, filed in the Hiroshima Tumor Tissue Registry between 1973 to 1985, only nine adenomas (TA-4, LA-5) or 0.3% were filed. All adenoma cases involved females, with an average of 27.4 years. Grossly, the tumors were found to vary from 1.5 to 5 cm in diameter and were sharply demarcated. Microscopically and ultrastructurally, the small tubules found in TA are identical to normal ducts. According to progress from pregnancy to lactation, the tubular tissue in LA demonstrate breast increasing secretory activities. The absence of TA during pregnancy, the structural similarity and the fact that some LA had already developed into a palpable mass before pregnancy are signs that indicate that all TA and LA share the same biologic process.
乳腺腺瘤是细胞性上皮病变，可分为两种类型，即管状腺瘤（TA）和泌乳性腺瘤（LA）。在1973年至1985年间登记于广岛肿瘤组织登记处的3365例乳腺良性上皮肿瘤（包括纤维腺瘤）中，仅有9例腺瘤（TA-4例，LA-5例）被登记，占0.3%。所有腺瘤病例均为女性，平均年龄27.4岁。大体上，肿瘤直径为1.5至5厘米，界限清晰。在显微镜和超微结构下，TA中发现的小导管与正常导管相同。根据从怀孕到哺乳的进展情况，LA中的管状组织显示出乳腺分泌活动增强。孕期未出现TA、结构相似以及一些LA在怀孕前就已发展为可触及肿块这一事实，均表明所有TA和LA具有相同的生物学过程。
