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撤回:微小RNA-139-5p通过减少组蛋白去乙酰化酶4(HDAC4)和激活BCL-2减轻缺氧缺血性脑损伤中的神经功能缺损。

RETRACTED: microRNA-139-5p alleviates neurological deficit in hypoxic-ischemic brain damage via HDAC4 depletion and BCL-2 activation.

作者信息

Fei Shinuan, Cao Lichun, Li Sheng

机构信息

Department of Pediatrics, Edong Healthcare Group, Huangshi Maternity and Children's Health Hospital, Huangshi, 435000, Hubei, PR China.

Department of Medical Customer Service, Huangshi Central Hospital•Affiliated Hospital of Hubei Polytechnic University, No. 293, Yiyuan Street, XiSaiShan District, Huangshi, 435000, Hubei, PR China.

出版信息

Brain Res Bull. 2021 Apr;169:73-80. doi: 10.1016/j.brainresbull.2020.12.020. Epub 2021 Jan 2.

Abstract

This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy). This article has been retracted at the request of the Editor-in-Chief as there are concerns about the reliability of the results. Concerns have been raised about the western blot bands in Figs. 5A, 6D having the same eyebrow shaped phenotype as found in many other publications as tabulated here (https://docs.google.com/spreadsheets/d/149EjFXVxpwkBXYJOnOHb6RhAqT4a2llhj9LM60MBffM/edit#gid=0). The journal requested the corresponding author to comment on these concerns and send the raw data, however the author was not able to provide uncropped images of the original gels. The Editor-in-Chief therefore no longer has confidence in the data and conclusions of this study.

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