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撤回:通过促进 microRNA-9-5p 并下调靶向蛋白,白细胞介素-1β 的抑制在阿尔茨海默病中发挥保护作用,靶向蛋白为非洲爪蟾类驱动蛋白样蛋白 2。

RETRACTED: Inhibition of interleukin-1β plays a protective role in Alzheimer's disease by promoting microRNA-9-5p and downregulating targeting protein for xenopus kinesin-like protein 2.

机构信息

College of Nursing, Inner Mongolia University for Nationalities, Tongliao 028000, Inner Mongolia Autonomous Region, PR China; Institute of Dementia, Inner Mongolia University for Nationalities, Tongliao 028000, Inner Mongolia, PR China.

Institute of Dementia, Inner Mongolia University for Nationalities, Tongliao 028000, Inner Mongolia, PR China; Inner Mongolia Key Laboratory of Mongolian Medicine Pharmacology for Cardio-Cerebral Vascular System, Tongliao 028000, Inner Mongolia, PR China.

出版信息

Int Immunopharmacol. 2021 Aug;97:107578. doi: 10.1016/j.intimp.2021.107578. Epub 2021 Apr 20.

Abstract

This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy). This article has been retracted at the request of the Editor-in-Chief. Concern was raised about the reliability of the Western blot results in Figs. 2C, 4C, and 5B+E, which appear to have the same eyebrow shaped phenotype as many other publications tabulated here (https://docs.google.com/spreadsheets/d/149EjFXVxpwkBXYJOnOHb6RhAqT4a2llhj9LM60MBffM/edit#gid=0 [docs.google.com]). The journal requested the corresponding author comment on these concerns and provide the raw data. However the authors were not able to satisfactorily fulfil this request and therefore the Editor-in-Chief decided to retract the article.

摘要

本文已被撤回

请参阅爱思唯尔关于文章撤回的政策(http://www.elsevier.com/locate/withdrawalpolicy)。应主编要求,本文已被撤回。人们对图 2C、4C 和 5B+E 中的 Western blot 结果的可靠性提出了质疑,这些结果似乎与这里列出的许多其他出版物(https://docs.google.com/spreadsheets/d/149EjFXVxpwkBXYJOnOHb6RhAqT4a2llhj9LM60MBffM/edit#gid=0 [docs.google.com])具有相同的眉毛形状表型。期刊要求通讯作者对这些问题发表评论并提供原始数据。然而,作者未能令人满意地满足这一要求,因此主编决定撤回这篇文章。

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