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乳铁蛋白:一种参与免疫调节、抗癌和抗菌过程的糖蛋白。

Lactoferrin: A Glycoprotein Involved in Immunomodulation, Anticancer, and Antimicrobial Processes.

机构信息

Laboratorio de Biotecnología I, Facultad de Ciencias Químicas, Universidad Autónoma de Chihuahua, Circuito Universitario s/n Campus Universitario 2, Chihuahua C.P. 31125, Mexico.

出版信息

Molecules. 2021 Jan 3;26(1):205. doi: 10.3390/molecules26010205.

DOI:10.3390/molecules26010205
PMID:33401580
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7795860/
Abstract

Lactoferrin is an iron binding glycoprotein with multiple roles in the body. Its participation in apoptotic processes in cancer cells, its ability to modulate various reactions of the immune system, and its activity against a broad spectrum of pathogenic microorganisms, including respiratory viruses, have made it a protein of broad interest in pharmaceutical and food research and industry. In this review, we have focused on describing the most important functions of lactoferrin and the possible mechanisms of action that lead to its function.

摘要

乳铁蛋白是一种铁结合糖蛋白,在体内具有多种作用。它参与癌细胞的凋亡过程,能够调节免疫系统的各种反应,并且对包括呼吸道病毒在内的广泛的病原微生物具有活性,这使得它成为了药物和食品研究和工业中广泛关注的一种蛋白质。在这篇综述中,我们重点描述了乳铁蛋白的最重要功能及其可能的作用机制。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed07/7795860/8aaa94d20197/molecules-26-00205-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed07/7795860/3e94118c9153/molecules-26-00205-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed07/7795860/29a20be72e4d/molecules-26-00205-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed07/7795860/665096ec66bd/molecules-26-00205-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed07/7795860/8aaa94d20197/molecules-26-00205-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed07/7795860/3e94118c9153/molecules-26-00205-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed07/7795860/29a20be72e4d/molecules-26-00205-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed07/7795860/665096ec66bd/molecules-26-00205-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed07/7795860/8aaa94d20197/molecules-26-00205-g004.jpg

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The Role of Lactoferrin in Combating spp. Infections Through Regulation of Oxidative Stress, Immune Response, and Nutritional Support in Women and Newborns.乳铁蛋白在通过调节氧化应激、免疫反应以及为妇女和新生儿提供营养支持来对抗 spp. 感染中的作用。
Molecules. 2025 May 31;30(11):2416. doi: 10.3390/molecules30112416.
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