Chen Shih-Wei, Tsai Stella Chin-Shaw, Chang Kuang-Hsi, Chuang Kai-Cheng, Sufian Muhammad, Fan Hueng-Chuen, Chen Chuan-Mu
Department of Otolaryngology, Tungs' Taichung MetroHarbor Hospital, Taichung 435, Taiwan.
Ph.D. Program in Translational Medicine, Department of Life Sciences, National Chung Hsing University, Taichung 402, Taiwan.
Nutrients. 2025 Feb 27;17(5):829. doi: 10.3390/nu17050829.
Air pollution, particularly particulate matter (PM), poses a significant health risk worldwide, with rhinitis emerging as a prevalent respiratory condition. This review explores the association between air pollution and rhinitis, focusing on PM-induced inflammation and the potential preventive role of nutritional supplements. A comprehensive literature search was conducted using the PubMed and Scopus databases, covering studies from inception to 2024 that investigated air pollution, rhinitis, and nutritional interventions. This review synthesizes evidence linking PM exposure to increased prevalence and exacerbation of rhinitis through various inflammatory mechanisms. We further examine the potential of nutritional supplements, including kefir peptides, lactoferrin, vitamin D, polyunsaturated fatty acids, and probiotics, in mitigating PM-induced inflammation and rhinitis symptoms. However, the evidence regarding the role of these supplements in modulating immune responses and reducing inflammation related to PM-induced rhinitis is limited. This review highlights the potential efficacy of nutritional interventions in preventing and managing air pollution-associated rhinitis, offering a complementary approach to environmental regulations in addressing this public health challenge.
空气污染，尤其是颗粒物（PM），在全球范围内构成了重大的健康风险，鼻炎已成为一种常见的呼吸道疾病。本综述探讨了空气污染与鼻炎之间的关联，重点关注PM引起的炎症以及营养补充剂的潜在预防作用。使用PubMed和Scopus数据库进行了全面的文献检索，涵盖了从开始到2024年调查空气污染、鼻炎和营养干预的研究。本综述综合了证据，表明通过各种炎症机制，接触PM会导致鼻炎患病率增加和病情加重。我们进一步研究了营养补充剂的潜力，包括开菲尔肽、乳铁蛋白、维生素D、多不饱和脂肪酸和益生菌，它们在减轻PM引起的炎症和鼻炎症状方面的作用。然而，关于这些补充剂在调节免疫反应和减少与PM引起的鼻炎相关炎症方面的作用的证据有限。本综述强调了营养干预在预防和管理与空气污染相关的鼻炎方面的潜在功效，为应对这一公共卫生挑战的环境法规提供了一种补充方法。
