• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

心血管磁共振成像：新兴技术与应用。

Cardiovascular magnetic resonance imaging: emerging techniques and applications.

机构信息

Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, West Yorkshire, UK.

Cardiovascular and Metabolic Medicine Group, University of East Anglia, Norwich, UK.

出版信息

Heart. 2021 May;107(9):697-704. doi: 10.1136/heartjnl-2019-315669. Epub 2021 Jan 5.

DOI:10.1136/heartjnl-2019-315669
PMID:33402364
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7611390/
Abstract

This review gives examples of emerging cardiovascular magnetic resonance (CMR) techniques and applications that have the potential to transition from research to clinical application in the near future. Four-dimensional flow CMR (4D-flow CMR) allows time-resolved three-directional, three-dimensional (3D) velocity-encoded phase-contrast imaging for 3D visualisation and quantification of valvular or intracavity flow. Acquisition times of under 10 min are achievable for a whole heart multidirectional data set and commercial software packages are now available for data analysis, making 4D-flow CMR feasible for inclusion in clinical imaging protocols. Diffusion tensor imaging (DTI) is based on the measurement of molecular water diffusion and uses contrasting behaviour in the presence and absence of boundaries to infer tissue structure. Cardiac DTI is capable of non-invasively phenotyping the 3D micro-architecture within a few minutes, facilitating transition of the method to clinical protocols. Hybrid positron emission tomography-magnetic resonance (PET-MR) provides quantitative PET measures of biological and pathological processes of the heart combined with anatomical, morphological and functional CMR imaging. Cardiac PET-MR offers opportunities in ischaemic, inflammatory and infiltrative heart disease.

摘要

这篇综述介绍了一些新兴的心血管磁共振（CMR）技术和应用，它们有可能在不久的将来从研究转化为临床应用。四维血流 CMR（4D-flow CMR）允许对瓣膜或心腔内的三维（3D）速度编码的相位对比成像进行时间分辨的三维（3D）方向流速测量，用于 3D 可视化和量化。整个心脏多方向数据集的采集时间可在 10 分钟以内完成，并且现在有商业软件包可用于数据分析，这使得 4D-flow CMR 可以纳入临床成像方案。扩散张量成像（DTI）基于分子水扩散的测量，利用边界存在和不存在时的对比行为来推断组织结构。心脏 DTI 能够在几分钟内无创地对 3D 微观结构进行表型分析，从而促进该方法向临床方案的转变。正电子发射断层扫描-磁共振（PET-MR）融合提供了心脏的生物学和病理过程的定量 PET 测量，结合了解剖学、形态学和功能 CMR 成像。心脏 PET-MR 在缺血性、炎症性和浸润性心脏病方面提供了机会。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8167/7611390/14e2881ef40d/EMS130993-f006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8167/7611390/e9fa905e6baf/EMS130993-f001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8167/7611390/7a46e70d7605/EMS130993-f002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8167/7611390/f0fb4aa3c678/EMS130993-f003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8167/7611390/520b5b54b915/EMS130993-f004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8167/7611390/84f908cf0702/EMS130993-f005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8167/7611390/14e2881ef40d/EMS130993-f006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8167/7611390/e9fa905e6baf/EMS130993-f001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8167/7611390/7a46e70d7605/EMS130993-f002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8167/7611390/f0fb4aa3c678/EMS130993-f003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8167/7611390/520b5b54b915/EMS130993-f004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8167/7611390/84f908cf0702/EMS130993-f005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8167/7611390/14e2881ef40d/EMS130993-f006.jpg

相似文献

1
Cardiovascular magnetic resonance imaging: emerging techniques and applications.心血管磁共振成像：新兴技术与应用。
Heart. 2021 May;107(9):697-704. doi: 10.1136/heartjnl-2019-315669. Epub 2021 Jan 5.
2
Novel Insights into Complex Cardiovascular Pathologies using 4D Flow Analysis by Cardiovascular Magnetic Resonance Imaging.使用心血管磁共振成像的 4D 流分析技术深入了解复杂心血管病理。
Curr Pharm Des. 2017;23(22):3262-3267. doi: 10.2174/1381612823666170317144257.
3
Comprehensive 4D velocity mapping of the heart and great vessels by cardiovascular magnetic resonance.心血管磁共振全面 4D 速度图绘制心脏和大血管。
J Cardiovasc Magn Reson. 2011 Jan 14;13(1):7. doi: 10.1186/1532-429X-13-7.
4
Clinical applications of intra-cardiac four-dimensional flow cardiovascular magnetic resonance: A systematic review.心脏内四维血流心血管磁共振的临床应用：系统评价。
Int J Cardiol. 2017 Dec 15;249:486-493. doi: 10.1016/j.ijcard.2017.07.023. Epub 2017 Sep 28.
5
Atlas-based analysis of 4D flow CMR: automated vessel segmentation and flow quantification.基于图谱的4D流心脏磁共振成像分析：自动血管分割与血流定量
J Cardiovasc Magn Reson. 2015 Oct 5;17:87. doi: 10.1186/s12968-015-0190-5.
6
Cardiac 4D phase-contrast CMR at 9.4 T using self-gated ultra-short echo time (UTE) imaging.使用自门控超短回波时间（UTE）成像的9.4T心脏4D相衬磁共振成像。
J Cardiovasc Magn Reson. 2017 Mar 31;19(1):39. doi: 10.1186/s12968-017-0351-9.
7
Real-time phase-contrast flow cardiovascular magnetic resonance with low-rank modeling and parallel imaging.基于低秩建模和平行成像的实时相衬血流心血管磁共振成像
J Cardiovasc Magn Reson. 2017 Feb 10;19(1):19. doi: 10.1186/s12968-017-0330-1.
8
Cardiovascular function and flow by 4-dimensional magnetic resonance imaging techniques: new applications.四维磁共振成像技术在心血管功能与血流方面的应用：新进展
J Thorac Imaging. 2014 May;29(3):185-96. doi: 10.1097/RTI.0000000000000068.
9
Clinical intra-cardiac 4D flow CMR: acquisition, analysis, and clinical applications.临床心内 4D 流心脏磁共振：采集、分析及临床应用。
Eur Heart J Cardiovasc Imaging. 2022 Jan 24;23(2):154-165. doi: 10.1093/ehjci/jeab112.
10
Improving visualization of 4D flow cardiovascular magnetic resonance with four-dimensional angiographic data: generation of a 4D phase-contrast magnetic resonance CardioAngiography (4D PC-MRCA).利用四维血管造影数据改善四维血流心血管磁共振成像：生成四维相位对比磁共振心血管造影（4D PC-MRCA）。
J Cardiovasc Magn Reson. 2017 Jun 23;19(1):47. doi: 10.1186/s12968-017-0360-8.

引用本文的文献

1
Factors Affecting the Quality of Non-contrast Coronary Magnetic Resonance Angiography Images: Challenges and Change.影响非对比剂冠状动脉磁共振血管造影图像质量的因素：挑战与变革
Rev Cardiovasc Med. 2025 Aug 19;26(8):37487. doi: 10.31083/RCM37487. eCollection 2025 Aug.
2
In Vivo Dynamic Coronary Arteries Blood Flow Imaging Based on Multi-Cycle Phase Clustering Ultrafast Ultrasound.基于多周期相位聚类超快超声的体内动态冠状动脉血流成像
Adv Sci (Weinh). 2025 Aug;12(31):e05485. doi: 10.1002/advs.202505485. Epub 2025 Jun 30.
3
Dynamic Velocity Tracking in the Left-Ventricular Outflow Track Using Four-Dimensional 4D Flow for the Assessment of Left Ventricular Outflow Track Obstruction.

本文引用的文献

1
Assessment of mitral valve regurgitation by cardiovascular magnetic resonance imaging.心血管磁共振成像评估二尖瓣反流。
Nat Rev Cardiol. 2020 May;17(5):298-312. doi: 10.1038/s41569-019-0305-z. Epub 2019 Dec 9.
2
Cardiovascular F-fluoride positron emission tomography-magnetic resonance imaging: A comparison study.心血管 F-氟正电子发射断层扫描-磁共振成像：一项比较研究。
J Nucl Cardiol. 2021 Oct;28(5):1-12. doi: 10.1007/s12350-019-01962-y. Epub 2019 Dec 2.
3
Identification of Myocardial Disarray in Patients With Hypertrophic Cardiomyopathy and Ventricular Arrhythmias.
使用四维（4D）血流对左心室流出道进行动态速度追踪以评估左心室流出道梗阻
Clin Case Rep. 2025 Apr 21;13(4):e70465. doi: 10.1002/ccr3.70465. eCollection 2025 Apr.
4
Cardiac Magnetic Resonance Imaging in Diagnostics and Cardiovascular Risk Assessment.心脏磁共振成像在诊断和心血管风险评估中的应用
Diagnostics (Basel). 2025 Jan 14;15(2):178. doi: 10.3390/diagnostics15020178.
5
Recent Progress of Cardiac MRI for Nuclear Medicine Professionals.核医学专业人员的心脏磁共振成像最新进展
Nucl Med Mol Imaging. 2024 Dec;58(7):431-448. doi: 10.1007/s13139-024-00850-9. Epub 2024 Feb 14.
6
The influence of post-processing software on quantitative results in 4D flow cardiovascular magnetic resonance examinations.后处理软件对四维流动心血管磁共振检查定量结果的影响。
Front Cardiovasc Med. 2024 Sep 27;11:1465554. doi: 10.3389/fcvm.2024.1465554. eCollection 2024.
7
Cardiac magnetic resonance imaging in systemic sclerosis: Heart involvement in high-resolution.系统性硬化症的心脏磁共振成像：高分辨率下的心脏受累情况
Rheumatol Immunol Res. 2024 Jul 15;5(2):83-92. doi: 10.1515/rir-2024-0011. eCollection 2024 Jun.
8
Emerging Concepts of Mechanisms Controlling Cardiac Tension: Focus on Familial Dilated Cardiomyopathy (DCM) and Sarcomere-Directed Therapies.控制心脏张力机制的新观念：聚焦家族性扩张型心肌病（DCM）和针对肌节的治疗方法
Biomedicines. 2024 May 2;12(5):999. doi: 10.3390/biomedicines12050999.
9
Is it aortic stenosis or left ventricular outflow tract obstruction? The complementary role of four-dimensional flow cardiac magnetic resonance imaging.是主动脉瓣狭窄还是左心室流出道梗阻？四维血流心脏磁共振成像的辅助作用。
Eur Heart J Case Rep. 2023 Sep 1;7(9):ytad436. doi: 10.1093/ehjcr/ytad436. eCollection 2023 Sep.
10
Feasibility of Wave Intensity Analysis from 4D Cardiovascular Magnetic Resonance Imaging Data.基于四维心血管磁共振成像数据的波强度分析的可行性
Bioengineering (Basel). 2023 May 31;10(6):662. doi: 10.3390/bioengineering10060662.
识别肥厚型心肌病伴室性心律失常患者的心肌错构。
J Am Coll Cardiol. 2019 May 28;73(20):2493-2502. doi: 10.1016/j.jacc.2019.02.065.
4
Assessment of Myocardial Viability in Ischemic Heart Disease by PET/MRI: Comparison of Left Ventricular Perfusion, Hibernation, and Scar Burden.采用 PET/MRI 评估缺血性心脏病的心肌活力：左心室灌注、冬眠和瘢痕负荷的比较。
Acad Radiol. 2020 Feb;27(2):188-197. doi: 10.1016/j.acra.2019.03.021. Epub 2019 Apr 30.
5
Same day comparison of PET/CT and PET/MR in patients with cardiac sarcoidosis.同日比较 PET/CT 和 PET/MR 在心脏结节病患者中的应用。
J Nucl Cardiol. 2020 Dec;27(6):2118-2129. doi: 10.1007/s12350-018-01578-8. Epub 2019 Jan 2.
6
Validation and reproducibility of cardiovascular 4D-flow MRI from two vendors using 2 × 2 parallel imaging acceleration in pulsatile flow phantom and in vivo with and without respiratory gating.使用2×2并行成像加速技术，在脉动流模体以及有和没有呼吸门控的活体中，对两家供应商的心血管4D流磁共振成像进行验证和可重复性研究。
Acta Radiol. 2019 Mar;60(3):327-337. doi: 10.1177/0284185118784981. Epub 2018 Jun 26.
7
Automated Cardiac Valve Tracking for Flow Quantification with Four-dimensional Flow MRI.基于四维血流磁共振的自动心脏瓣膜追踪技术用于流量量化。
Radiology. 2019 Jan;290(1):70-78. doi: 10.1148/radiol.2018180807. Epub 2018 Oct 30.
8
Impact of Age and Diastolic Function on Novel, 4D flow CMR Biomarkers of Left Ventricular Blood Flow Kinetic Energy.年龄和舒张功能对左心室血流动力学能量的新型 4D 流 CMR 生物标志物的影响。
Sci Rep. 2018 Sep 26;8(1):14436. doi: 10.1038/s41598-018-32707-5.
9
Left ventricular blood flow kinetic energy after myocardial infarction - insights from 4D flow cardiovascular magnetic resonance.心肌梗死后左心室血流动能 - 4D 流心血管磁共振的见解。
J Cardiovasc Magn Reson. 2018 Aug 30;20(1):61. doi: 10.1186/s12968-018-0483-6.
10
Five-minute whole-heart coronary MRA with sub-millimeter isotropic resolution, 100% respiratory scan efficiency, and 3D-PROST reconstruction.五 分 钟 全 心 冠 状 MRA，亚 毫 米 各 向 同 性 分 辨 率，100%呼 吸 扫 描 效 率，和 3D-PROST 重 建。
Magn Reson Med. 2019 Jan;81(1):102-115. doi: 10.1002/mrm.27354. Epub 2018 Jul 29.