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新冠病毒阳性患者伤口中未检测到严重急性呼吸综合征冠状病毒2:一项初步研究。

No Traces of SARS-CoV-2 In Wounds of COVID-19 Positive Patients: A Pilot Study.

作者信息

Gaba Sunil, Kampalli Gowtham, Goyal Kapil, Suri Vikas, Chauhan Poonam, Meena Shyam C, Bhatnagar Ankur, Singh Mini P, Sharma Ramesh K

机构信息

Department of Plastic Surgery, PGIMER, Chandigarh, India.

Department of Virology, PGIMER, Chandigarh, India.

出版信息

Indian J Plast Surg. 2020 Dec;53(3):399-401. doi: 10.1055/s-0040-1718852. Epub 2020 Oct 16.

DOI:10.1055/s-0040-1718852
PMID:33402771
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7775226/
Abstract

This study was performed to investigate the presence of SARS-CoV-2 virus in wounds of COVID-19 positive patients.  This is a single-center observational study. COVID-19 patients with wounds (traumatic/infective/surgical) were included in this study. Preoperative, intraoperative, or postoperative specimens were collected and analyzed with real-time reverse transcriptase polymerase chain reaction (rRT-PCR) to know the presence of the virus.  A total of eight patients were included in this study. Eleven samples were collected (seven wound swabs, two peritoneal fluids, and two tissue specimens) and analyzed. None of the samples from the wound tested positive for the virus while they were tested positive for nasal swab taken simultaneously or within 3 days prior.  The wounds of COVID-19 patients are considered negative and can be managed with routine wound precautions.

摘要

本研究旨在调查新型冠状病毒肺炎(COVID-19)阳性患者伤口中是否存在严重急性呼吸综合征冠状病毒2(SARS-CoV-2)病毒。 这是一项单中心观察性研究。本研究纳入了有伤口(创伤性/感染性/手术性)的COVID-19患者。收集术前、术中和术后标本,并采用实时逆转录聚合酶链反应(rRT-PCR)进行分析,以了解病毒的存在情况。 本研究共纳入8例患者。收集了11份样本(7份伤口拭子、2份腹腔积液和2份组织标本)并进行分析。伤口样本中没有一份病毒检测呈阳性,而同时采集或在之前3天内采集的鼻拭子检测呈阳性。 COVID-19患者的伤口被视为阴性,可采取常规伤口预防措施进行处理。

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IDCases. 2020 May 21;21:e00836. doi: 10.1016/j.idcr.2020.e00836. eCollection 2020.
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Severe Acute Respiratory Syndrome Coronavirus 2 RNA Detected in Blood Donations.血标本中检测到严重急性呼吸综合征冠状病毒 2 型 RNA。
Emerg Infect Dis. 2020 Jul;26(7):1631-1633. doi: 10.3201/eid2607.200839. Epub 2020 Jun 21.
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Detection of SARS-CoV-2 in Different Types of Clinical Specimens.SARS-CoV-2 在不同类型临床标本中的检测。
JAMA. 2020 May 12;323(18):1843-1844. doi: 10.1001/jama.2020.3786.
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A Novel Coronavirus from Patients with Pneumonia in China, 2019.2019 年中国肺炎患者中的一种新型冠状病毒。
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