尼日利亚哈科特港地区消化性溃疡疾病的现状。

Current status of peptic ulcer disease in Port Harcourt metropolis, Nigeria.

机构信息

Digestive Disease Unit, Oak Endoscopy Centre Port Harcourt.

Department of Surgery, University of Port Harcourt Teaching Hospital Port Harcourt, Rivers State, Nigeria.

出版信息

Afr Health Sci. 2020 Sep;20(3):1446-1451. doi: 10.4314/ahs.v20i3.50.

DOI:10.4314/ahs.v20i3.50

PMID:33402993

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7751553/

Abstract

BACKGROUND

Epidemiological studies on peptic ulcer disease (PUD) have shown a recent decrease in hospital admissions in Western countries.

OBJECTIVE

This paper aimed to study the current status and risk factors of PUD in a Nigerian metropolis.

METHODS

A cross-sectional study of symptomatic patients at upper gastrointestinal (GI) endoscopy diagnosed with PUD from February 2014 to September 2019 at a referral endoscopy facility in Port Harcourt, Niger delta region of Nigeria. The variables studied included demographics, symptoms and duration, blood group, chronic non-steroidal anti-inflammatory (NSAID) use, smoking, endoscopic and histology findings. Statistical analysis was performed using SPSS version 20.

RESULTS

A total of 434 upper GI endoscopies were performed during the study period with thirty-one diagnosis of PUD made. The mean age of gastric ulcer (GU) and duodenal ulcer (DU) cases were 54.4 ± 20.2yrs and 48.1 ± 14.5yrs respectively (p = 0.367). GU to DU ratio was 1.4:1. infection, chronic NSAID use and blood group O were seen in 7(22.5%), 8(25.8%) and 18(72.0%) respectively. Major indication in 21(67.7%) cases was gastrointestinal bleeding.

CONCLUSION

There is a low diagnostic rate of PUD (6.7%) with pre-pyloric antral gastric ulcers as most common type and multifactorial aetiology.

摘要

背景

消化性溃疡病（PUD）的流行病学研究表明，西方国家的住院人数近期有所下降。

目的

本文旨在研究尼日利亚大都市中 PUD 的现状和危险因素。

方法

这是一项在尼日利亚尼日尔三角洲地区哈科特港的一家转诊内镜机构进行的、针对因上消化道（GI）症状而行内镜检查并确诊为 PUD 的患者的横断面研究。研究的变量包括人口统计学、症状和持续时间、血型、慢性非甾体抗炎药（NSAID）使用、吸烟、内镜和组织学发现。使用 SPSS 版本 20 进行统计分析。

结果

在研究期间共进行了 434 次上 GI 内镜检查，其中 31 例诊断为 PUD。胃溃疡（GU）和十二指肠溃疡（DU）患者的平均年龄分别为 54.4 ± 20.2 岁和 48.1 ± 14.5 岁（p = 0.367）。GU 与 DU 的比例为 1.4:1。感染、慢性 NSAID 使用和血型 O 在 7（22.5%）、8（25.8%）和 18（72.0%）例中分别可见。21（67.7%）例的主要指征为胃肠道出血。