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住院吸烟者慢性阻塞性肺疾病的主动筛查——一项可行性研究。

Active screening for COPD among hospitalized smokers - a feasibility study.

作者信息

Mycroft Katarzyna, Korczynski Piotr, Jankowski Piotr, Kutka Mikolaj, Zelazna Olga, Zagaja Marcin, Wozniczko Kornelia, Szafranska Urszula, Koltowski Lukasz, Opolski Grzegorz, Krenke Rafal, Gorska Katarzyna

机构信息

Department of Internal Medicine, Pulmonary Diseases and Allergy, Medical University of Warsaw, Warsaw, Poland.

Students' Research Group "Alveolus", Medical University of Warsaw, Warsaw, Poland.

出版信息

Ther Adv Chronic Dis. 2020 Dec 14;11:2040622320971111. doi: 10.1177/2040622320971111. eCollection 2020.

Abstract

BACKGROUND

Spirometry is a primary tool for early chronic obstructive pulmonary disease (COPD) detection in patients with risk factors, for example, cigarette smoking. The aim of this study was to evaluate the strategy of an active screening for COPD among smokers admitted to the pulmonary and cardiology department.

METHODS

This prospective study was conducted between February and March 2019. All hospitalized smokers aged 40 years and older completed an original questionnaire and had spirometry measurement with a bronchial reversibility test (if applicable) performed by medical students using a portable spirometer.

RESULTS

One hundred and eighty-eight patients were eligible to participate in the study. Seventy (37%) subjects refused to participate. Eventually, 116 (62%) patients were included in the final analysis and 94 (81%) performed spirometry correctly. In total, 32 (34 %) patients were found to have COPD. Nine (28%) of these patients were newly diagnosed, 89% of them had mild-to-moderate airway obstruction. Patients with newly diagnosed COPD were significantly younger [age 63 (56-64) 69 (64-78) years], had a longer smoking-free period [17 (13-20) 9 (2-12) years], had fewer symptoms and had a better lung function compared with patients with a previous diagnosis of COPD ( < 0.05 for all comparisons).

CONCLUSION

The proposed diagnostic strategy can be successfully used to improve COPD detection in the inpatient setting. The majority of the newly diagnosed COPD patients had mild-to-moderate airway obstruction. Patients who should be particularly screened for COPD include ex-smokers with less pronounced respiratory symptoms.

摘要

背景

肺量计检查是对有危险因素(如吸烟)的患者进行慢性阻塞性肺疾病(COPD)早期检测的主要工具。本研究的目的是评估对入住肺病科和心脏病科的吸烟者进行COPD主动筛查的策略。

方法

本前瞻性研究于2019年2月至3月进行。所有40岁及以上住院吸烟者均完成一份原始问卷,并由医学生使用便携式肺量计进行肺量计测量及支气管可逆性试验(如适用)。

结果

188例患者符合参与研究的条件。70例(37%)受试者拒绝参与。最终,116例(62%)患者纳入最终分析,94例(81%)正确完成肺量计测量。总共发现32例(34%)患者患有COPD。其中9例(28%)为新诊断患者,89%为轻度至中度气道阻塞。与既往诊断为COPD的患者相比,新诊断为COPD的患者明显更年轻[年龄63(56 - 64)对69(64 - 78)岁],戒烟时间更长[17(13 - 20)对9(2 - 12)年],症状更少,肺功能更好(所有比较P < 0.05)。

结论

所提出的诊断策略可成功用于改善住院患者中COPD的检测。大多数新诊断的COPD患者为轻度至中度气道阻塞。应特别进行COPD筛查的患者包括呼吸道症状不明显的既往吸烟者。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d87c/7739207/16bc8501df80/10.1177_2040622320971111-fig1.jpg

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