Suppr超能文献

退伍军人事务部退伍军人药物基因组检测(PHASER)临床项目。

Veterans Affairs Pharmacogenomic Testing for Veterans (PHASER) clinical program.

作者信息

Dong Olivia M, Bates Jill, Chanfreau-Coffinier Catherine, Naglich Michael, Kelley Michael J, Meyer Laurence J, Icardi Michael, Vassy Jason L, Sriram Peruvemba, Heise Craig William, Rivas Salvador, Ribeiro Maria, Jacobitz Russell, Rozelle Susan, Chapman Jennifer G, Voora Deepak

机构信息

Durham VA Health Care System, Durham, NC 27705, USA.

Department of Medicine, Duke Center for Applied Genomics & Precision Medicine, Duke University School of Medicine, Durham, NC 27708, USA.

出版信息

Pharmacogenomics. 2021 Feb;22(3):137-144. doi: 10.2217/pgs-2020-0173. Epub 2021 Jan 6.

Abstract

In 2019, the Veterans Affairs (VA), the largest integrated US healthcare system, started the Pharmacogenomic Testing for Veterans (PHASER) clinical program that provides multi-gene pharmacogenomic (PGx) testing for up to 250,000 veterans at approximately 50 sites. PHASER is staggering program initiation at sites over a 5-year period from 2019 to 2023, as opposed to simultaneous initiation at all sites, to facilitate iterative program quality improvements through Plan-Do-Study-Act cycles. Current resources in the PGx field have not focused on multisite, remote implementation of panel-based PGx testing. In addition to bringing large scale PGx testing to veterans, the PHASER program is developing a roadmap to maximize uptake and optimize the use of PGx to improve drug response outcomes.

摘要

2019年,美国最大的综合性医疗系统退伍军人事务部(VA)启动了退伍军人药物基因组检测(PHASER)临床项目,该项目在约50个地点为多达25万名退伍军人提供多基因药物基因组(PGx)检测。PHASER计划在2019年至2023年的5年时间内在各地点逐步启动项目,而不是在所有地点同时启动,以便通过计划-执行-研究-行动循环促进项目质量的迭代改进。目前PGx领域的资源尚未集中于基于检测板的PGx检测的多地点远程实施。除了为退伍军人提供大规模的PGx检测外,PHASER项目还在制定路线图,以最大限度地提高接受率并优化PGx的使用,从而改善药物反应结果。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验