State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources; College of Life Sciences, South China Agricultural University, Guangzhou 510642, China.
Guangdong Laboratory for Lingnan Modern Agriculture, Guangzhou 510642, China.
Plant Commun. 2019 Dec 24;1(1):100017. doi: 10.1016/j.xplc.2019.100017. eCollection 2020 Jan 13.
Nutrient deficiencies in crops are a serious threat to human health, especially for populations in poor areas. To overcome this problem, the development of crops with nutrient-enhanced traits is imperative. Biofortification of crops to improve nutritional quality helps combat nutrient deficiencies by increasing the levels of specific nutrient components. Compared with agronomic practices and conventional plant breeding, plant metabolic engineering and synthetic biology strategies are more effective and accurate in synthesizing specific micronutrients, phytonutrients, and/or bioactive components in crops. In this review, we discuss recent progress in the field of plant synthetic metabolic engineering, specifically in terms of research strategies of multigene stacking tools and engineering complex metabolic pathways, with a focus on improving traits related to micronutrients, phytonutrients, and bioactive components. Advances and innovations in plant synthetic metabolic engineering would facilitate the development of nutrient-enriched crops to meet the nutritional needs of humans.
作物营养缺乏是对人类健康的严重威胁，特别是对贫困地区的人口。为了克服这个问题，开发具有增强营养特性的作物势在必行。通过增加特定营养成分的水平，对作物进行生物强化以改善其营养质量有助于对抗营养缺乏。与农业实践和传统植物育种相比，植物代谢工程和合成生物学策略在合成作物中的特定微量营养素、植物营养素和/或生物活性成分方面更有效和准确。在这篇综述中，我们讨论了植物合成代谢工程领域的最新进展，特别是在多基因堆叠工具的研究策略和复杂代谢途径的工程方面，重点是改善与微量营养素、植物营养素和生物活性成分相关的特性。植物合成代谢工程的进展和创新将促进营养丰富作物的发展，以满足人类的营养需求。
