Sirinavin S, Jayanetra P, Lolekha S, Layangkul T
Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Pediatr Infect Dis J. 1988 Jan;7(1):44-8. doi: 10.1097/00006454-198801000-00011.
To identify the risks and predictors for extraintestinal Salmonella infection (ETI) in infants and children with nontyphoidal Salmonella enteritis, we performed a retrospective review of 326 infants and children with diarrhea and rectal swab cultures positive for nontyphoidal Salmonella enteritis seen at Ramathibodi Hospital between 1981 and 1983. Nineteen patients had bacteremia. The overall rate of bacteremia was 5.8% which was 24.3% of those having blood cultures taken. Salmonella typhimurium was the most common cause of ETI and the most invasive among the common serotypes causing enteritis. The clinical characteristics of the patients with high probabilities of having ETI were: younger than 6 months of age; high body temperature; and immunocompromising conditions. The observed frequency of ETI in these patients was 21.9 to 26.3% compared with 0 to 0.7% in patients without those risk factors.
为了确定非伤寒沙门氏菌肠炎患儿发生肠外沙门氏菌感染（ETI）的风险和预测因素，我们对1981年至1983年间在拉玛蒂博迪医院就诊的326例腹泻且直肠拭子培养非伤寒沙门氏菌肠炎呈阳性的婴幼儿和儿童进行了回顾性研究。19例患者发生菌血症。菌血症总体发生率为5.8%，占进行血培养患者的24.3%。鼠伤寒沙门氏菌是ETI最常见的病因，也是引起肠炎的常见血清型中最具侵袭性的。发生ETI可能性高的患者的临床特征为：年龄小于6个月；体温高；以及免疫功能低下。这些患者中观察到的ETI发生率为21.9%至26.3%，而无这些危险因素的患者中ETI发生率为0至0.7%。
