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建立自动化生物制造实验室。

Setting Up an Automated Biomanufacturing Laboratory.

机构信息

Lanzatech Inc., Skokie, IL, USA.

出版信息

Methods Mol Biol. 2021;2229:137-155. doi: 10.1007/978-1-0716-1032-9_5.

Abstract

Laboratory automation is a key enabling technology for genetic engineering that can lead to higher throughput, more efficient and accurate experiments, better data management and analysis, decrease in the DBT (Design, Build, and Test) cycle turnaround, increase of reproducibility, and savings in lab resources. Choosing the correct framework among so many options available in terms of software, hardware, and skills needed to operate them is crucial for the success of any automation project. This chapter explores the multiple aspects to be considered for the solid development of a biofoundry project including available software and hardware tools, resources, strategies, partnerships, and collaborations in the field needed to speed up the translation of research results to solve important society problems.

摘要

实验室自动化是基因工程的一项关键使能技术,可提高通量、提高实验的效率和准确性、改善数据管理和分析、缩短设计、构建和测试(DBT)周期、提高可重复性并节约实验室资源。在软件、硬件以及操作它们所需的技能方面,选择正确的框架对于任何自动化项目的成功都是至关重要的。本章探讨了在生物铸造厂项目的扎实开发中需要考虑的多个方面,包括可用的软件和硬件工具、资源、策略、合作伙伴关系和合作,以加速研究成果的转化,解决重要的社会问题。

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