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吸气肌训练对哮喘患者吸气肌功能、功能能力和生活质量的疗效:一项随机对照试验。

Efficacy of inspiratory muscle training on inspiratory muscle function, functional capacity, and quality of life in patients with asthma: A randomized controlled trial.

机构信息

Rehabilitation Sciences Program, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.

Faculdade Ciências Médicas de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.

出版信息

Clin Rehabil. 2021 Jun;35(6):870-881. doi: 10.1177/0269215520984047. Epub 2021 Jan 6.

DOI:10.1177/0269215520984047
PMID:33406892
Abstract

OBJECTIVE

To evaluate the efficacy of an inspiratory muscle training protocol on inspiratory muscle function, functional capacity, and quality of life in patients with asthma.

DESIGN

A single-blind, randomized controlled clinical trial.

SETTING

Community-based.

SUBJECTS

Patients with asthma, aged between 20 and 70 years old, non-smokers.

INTERVENTIONS

Participants were randomized into two groups: inspiratory muscle training group performed inspiratory muscle training 5 days a week for 8 weeks, consisting of six sets of 30 breaths per day with a training load ⩾50% of maximal inspiratory pressure, plus an educational program; the control group only received the educational program.

MAIN MEASUREMENTS

Maximal inspiratory pressure, inspiratory muscle endurance, and the distance performed on the incremental shuttle walking test were assessed pre-intervention, post-intervention and at follow-up (3 months after the end of the intervention). The asthma quality of life questionnaire was applied pre and post-intervention.

RESULTS

Data from 39 participants were analyzed. Maximal inspiratory pressure in percentage of predicted and endurance test duration were significantly higher post-intervention in the inspiratory muscle training group (∆ post-pre: 50.8% vs 7.3% of predicted -  < 0.001 and ∆ post-pre: 207.9 seconds vs 2.7 seconds -  < 0.001, respectively). There was no significant difference in the incremental shuttle walking distance between groups (∆ post-pre: 30.9 m vs -8.1 m,  = 0.165). Quality of life was perceived as significantly better, without a difference between groups ( > 0.05).

CONCLUSIONS

About 8 weeks of inspiratory muscle training in patients with controlled asthma significantly increased inspiratory muscle strength and endurance.

摘要

目的

评估吸气肌训练方案对哮喘患者吸气肌功能、功能能力和生活质量的疗效。

设计

单盲、随机对照临床试验。

地点

社区为基础。

对象

年龄在 20 至 70 岁之间、非吸烟者的哮喘患者。

干预措施

参与者被随机分为两组:吸气肌训练组每周进行 5 天的吸气肌训练,每天进行 6 组 30 次呼吸,训练负荷 ⩾50%最大吸气压力,外加教育计划;对照组仅接受教育计划。

主要测量

最大吸气压力、吸气肌耐力和递增穿梭步行测试的距离在干预前、干预后和随访(干预结束后 3 个月)进行评估。在干预前后应用哮喘生活质量问卷。

结果

对 39 名参与者的数据进行了分析。吸气肌训练组的最大吸气压力预测百分比和耐力测试持续时间在干预后显著升高(干预后与干预前的差异:50.8%比预测值的 7.3% -  < 0.001和 207.9 秒比 2.7 秒 -  < 0.001,分别)。两组之间递增穿梭步行距离没有显著差异(干预后与干预前的差异:30.9 米比 -8.1 米,  = 0.165)。生活质量被认为明显改善,但两组之间没有差异( > 0.05)。

结论

在控制良好的哮喘患者中进行约 8 周的吸气肌训练可显著提高吸气肌力量和耐力。

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