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一项为期六周的吸气肌训练和有氧运动可改善电视辅助胸腔镜手术后肺癌患者的呼吸肌力量和运动能力:一项随机对照试验。

A six-week inspiratory muscle training and aerobic exercise improves respiratory muscle strength and exercise capacity in lung cancer patients after video-assisted thoracoscopic surgery: A randomized controlled trial.

机构信息

Department of Respiratory Care, Chang Gung University of Science and Technology, Chiayi.

Department of Respiratory Therapy, Chang Gung Memorial Hospital-Kaohsiung Medical Center and Chang Gung University College of Medicine, Kaohsiung.

出版信息

Clin Rehabil. 2021 Jun;35(6):840-850. doi: 10.1177/0269215520980138. Epub 2020 Dec 14.

DOI:10.1177/0269215520980138
PMID:33307766
Abstract

OBJECTIVE

To compare the postoperative outcomes of inspiratory muscle training and aerobic exercise, along with standard care, on lung cancer patients undergoing video-assisted thoracoscopic surgery (VATS).

DESIGN

A parallel-group, single-blind randomized clinical trial.

SETTING

Thoracic surgery ward and outpatient clinic in a teaching hospital.

SUBJECTS

Overall 63 patients underwent VATS were randomly assigned to a triaging (TG,  32) or control group (CG,  31). A total of 54 patients (TG,  26; CG,  28) completed the study.

INTERVENTION

TG: six-week threshold inspiratory muscle training and aerobic exercise. CG: standard care.

MAIN MEASURES

Maximum inspiratory pressure (PImax), maximum expiratory pressure (PEmax) lung expansion volume, and 6-min walking test (6MWT) were performed on the day of chest tube removal (baseline), and 2, 6, and 12 weeks postoperatively.

RESULTS

The TG showed significant improvement in PImax at week 6 (71.6 ± 34.9 vs. 94.3 ± 32.8 cmHO,  = 0.018), PEmax at week 2 (70.9 ± 24.3 vs. 90.9 ± 28.2 cmHO,  = 0.015) and week 12 (76.1 ± 20.2 vs. 98.6 ± 35.3 cmHO,  = 0.012), the lung expansion volume at week 2 (1080 ± 433 vs 1457 ± 624 mL,  = 0.02) and week 12 (1200 ± 387 vs 1885 ± 678 mL,  < 0.001), in addition to the 6MWT at week 2 (332 ± 78 vs 412 ± 74 m,  = 0.002), week 6 (360 ± 70 vs 419 ± 60 m,  = 0.007) and week 12 (360 ± 58 vs 402 ± 65 m,  = 0.036).

CONCLUSION

A six weeks of inspiratory muscle training and aerobic exercise had improved respiratory muscle strength and aerobic exercise postoperatively in lung cancer patients after VATS as early as 2 weeks.

摘要

目的

比较吸气肌训练和有氧运动联合标准护理与单纯标准护理对接受电视辅助胸腔镜手术(VATS)的肺癌患者的术后效果。

设计

平行组、单盲随机临床试验。

地点

教学医院的胸外科病房和门诊。

受试者

共有 63 名接受 VATS 的患者被随机分配到分诊组(TG,32 名)或对照组(CG,31 名)。共有 54 名患者(TG,26 名;CG,28 名)完成了研究。

干预措施

TG:六周的阈吸气肌训练和有氧运动。CG:标准护理。

主要测量指标

在拔除胸腔引流管当天(基线)、术后 2、6 和 12 周时,进行最大吸气压力(PImax)、最大呼气压力(PEmax)、肺扩张量和 6 分钟步行试验(6MWT)。

结果

TG 在第 6 周时 PImax 显著改善(71.6 ± 34.9 比 94.3 ± 32.8 cmH2O,  = 0.018),第 2 周时 PEmax 显著改善(70.9 ± 24.3 比 90.9 ± 28.2 cmH2O,  = 0.015)和第 12 周时 PEmax 显著改善(76.1 ± 20.2 比 98.6 ± 35.3 cmH2O,  = 0.012),第 2 周时肺扩张量显著改善(1080 ± 433 比 1457 ± 624 mL,  = 0.02)和第 12 周时肺扩张量显著改善(1200 ± 387 比 1885 ± 678 mL,  < 0.001),此外,第 2 周时 6MWT 显著改善(332 ± 78 比 412 ± 74 m,  = 0.002),第 6 周时 6MWT 显著改善(360 ± 70 比 419 ± 60 m,  = 0.007)和第 12 周时 6MWT 显著改善(360 ± 58 比 402 ± 65 m,  = 0.036)。

结论

肺癌患者接受 VATS 术后 2 周即可进行 6 周的吸气肌训练和有氧运动,可尽早改善术后呼吸肌力量和有氧运动能力。

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