光学质量分析系统在轻度后囊膜混浊患者钕:钇铝石榴石激光后囊切开术中决策制定的效用。
Utility of the optical quality analysis system for decision-making in Nd: YAG laser posterior capsulotomy in patients with light posterior capsule opacity.
作者信息
Lu Bo, Zhu Weijie, Fan Yu, Shi Dong, Ma Liwei
机构信息
Department of Ophthalmology, the Fourth Affiliated Hospital of China Medical University, Eye Hospital of China Medical University, Shenyang City, 110005, Liaoning Province, China.
Aier Excellence Eye Hospital, Central South University Aier School of Ophthalmology, Shenyang City, 110001, Liaoning Province, China.
出版信息
BMC Ophthalmol. 2021 Jan 6;21(1):7. doi: 10.1186/s12886-020-01710-8.
BACKGROUND
A prospective cohort study was performed to evaluate whether the Optical Quality Analysis System (OQAS) can serve as a valuable additional indicator for appropriate posterior capsulotomy referral.
METHODS
One hundred and five eyes from 96 patients undergoing capsulotomy were divided into precapsulotomy logMAR CDVA ≤0.1 group and logMAR CDVA > 0.1 group. CDVA, and the Visual Function 14 index (VF-14) score were estimated before and 1 month after capsulotomy. The objective scattering index (OSI) value was measured by using the OQAS. Posterior capsule opacification (PCO) severity was assessed with Evaluation of PCO 2000 (EPCO 2000) software.
RESULTS
In logMAR CDVA > 0.1 group, the correlations of OSI, logMAR CDVA, EPCO score and VF-14 score were very strong preoperatively. In logMAR CDVA ≤0.1 group, preoperatively, OSI was correlated with logMAR CDVA (r = 0.451), EPCO score (r = 0.789), and VF-14 score (r = 0.852). LogMAR CDVA has weak correlation with VF-14 score (r = - 0.384) and EPCO score (r = 0.566). VF-14 score was correlated with EPCO score (r = - 0.669). In the logMAR CDVA ≤0.1 group, there was no significant difference in logMAR CDVA between precapsulotomy and postcapsulotomy (P > 0.05). In the two groups, all the other optical quality parameters were significantly improved after capsulotomy (P < 0.05). In logMAR CDVA > 0.1 group, the area under the curve of the ROC of the OSI was 0.996 (P = 0.000). In logMAR CDVA ≤0.1 group, the area under the curve of the ROC of the OSI was 0.943 (P = 0.000).
CONCLUSIONS
The OSI was useful for evaluating of PCO and prediction of beneficial capsulotomy. Especially for patients with slight PCO and better visual acuity, OSI is more valuable than CDVA and completely objective examination.
TRIAL REGISTRATION
The study protocol was registered at the Chinese Clinical Trial Registry. Register: ChiCTR1800018842 (Registered Date: October 13th, 2018).
背景
进行一项前瞻性队列研究，以评估光学质量分析系统（OQAS）能否作为后囊切开术合理转诊的有价值的附加指标。
方法
将96例接受囊切开术患者的105只眼分为囊切开术前logMAR最佳矫正视力（CDVA）≤0.1组和logMAR CDVA>0.1组。在囊切开术前和术后1个月评估CDVA和视觉功能14指标（VF-14）评分。使用OQAS测量客观散射指数（OSI）值。用后囊混浊（PCO）2000评估软件（EPCO 2000）评估PCO严重程度。
结果
在logMAR CDVA>0.1组中，术前OSI、logMAR CDVA、EPCO评分和VF-14评分之间的相关性非常强。在logMAR CDVA≤0.1组中，术前OSI与logMAR CDVA（r = 0.451）、EPCO评分（r = 0.789）和VF-14评分（r = 0.852）相关。LogMAR CDVA与VF-14评分（r = -0.384）和EPCO评分（r = 0.566）的相关性较弱。VF-14评分与EPCO评分相关（r = -0.669）。在logMAR CDVA≤0.1组中，囊切开术前和术后logMAR CDVA无显著差异（P>0.05）。在两组中，囊切开术后所有其他光学质量参数均有显著改善（P<0.05）。在logMAR CDVA>0.1组中，OSI的ROC曲线下面积为0.996（P = 0.000）。在logMAR CDVA≤0.1组中，OSI的ROC曲线下面积为0.943（P = 0.000）。
结论
OSI有助于评估PCO和预测囊切开术的益处。特别是对于PCO较轻且视力较好的患者，OSI比CDVA更有价值且是完全客观的检查。
试验注册
该研究方案已在中国临床试验注册中心注册。注册号：ChiCTR1800018842（注册日期：2018年10月13日）。
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