Department of Ophthalmology, Ya'an People's Hospital, No.9, Ankang Road, Yucheng District, Ya'an City, 625000, Sichuan Province, China.
Department of Ophthalmology, Chengdu Wodi Ophthalmology Hospital, Chengdu, China.
Int Ophthalmol. 2024 Aug 16;44(1):350. doi: 10.1007/s10792-024-03255-x.
To evaluate the predictive value of anterior segment optical coherence tomography (AS-OCT) for postoperative corneal edema in cataract patients.
A retrospective cohort study of 144 cataract patients from December 2020 to December 2021 was conducted. Patients were divided into edema eyes (84 cases) and observation (60 cases) group based on postoperative corneal edema occurrence. Relevant indicators were compared between groups. Logistic regression identified risk factors for postoperative corneal edema. Receiver operating characteristic curves evaluated the predictive value.
The edema eyes group had significantly higher postoperative central corneal thickness (CCT) and lower postoperative endothelial cell density (ECD) than the observation group (P < 0.05). The edema eyes group also had significantly lower preoperative ECD, anterior chamber depth (ACD), anterior chamber angle (ACA), and preoperative lens position (LP) than the observation group (P < 0.05). Logistic regression analysis showed that preoperative ECD, ACD, ACA, and LP were independent risk factors for postoperative corneal edema (P < 0.05), all of which also showed good predictive value for postoperative corneal edema, with areas under the curve (AUCs) of 0.854, 0.812, 0.791, and 0.778, respectively, under the ROC curve analysis.
AS-OCT can provide useful information for predicting postoperative corneal edema in cataract patients. Preoperative ECD, preoperative ACD, preoperative ACA, and preoperative LP are important parameters that can be measured by AS-OCT and used as risk factors for postoperative corneal edema.
评估眼前节光学相干断层扫描(AS-OCT)对白内障患者术后角膜水肿的预测价值。
对 2020 年 12 月至 2021 年 12 月期间的 144 例白内障患者进行回顾性队列研究。根据术后角膜水肿的发生情况,将患者分为水肿眼(84 例)和观察组(60 例)。比较两组的相关指标。采用 Logistic 回归分析确定术后角膜水肿的危险因素。采用受试者工作特征曲线(ROC 曲线)评估预测价值。
水肿眼组术后中央角膜厚度(CCT)明显高于观察组,术后内皮细胞密度(ECD)明显低于观察组(P<0.05)。水肿眼组的术前 ECD、前房深度(ACD)、前房角(ACA)和术前晶状体位置(LP)也明显低于观察组(P<0.05)。Logistic 回归分析显示,术前 ECD、ACD、ACA 和 LP 是术后角膜水肿的独立危险因素(P<0.05),ROC 曲线分析显示,它们对术后角膜水肿均具有良好的预测价值,曲线下面积(AUC)分别为 0.854、0.812、0.791 和 0.778。
AS-OCT 可为白内障患者术后角膜水肿的预测提供有价值的信息。术前 ECD、术前 ACD、术前 ACA 和术前 LP 是 AS-OCT 可测量的重要参数,可作为术后角膜水肿的危险因素。