Division of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine.
The Heart Institute, Cincinnati Children's Hospital Medical Center.
Circ J. 2021 Jun 25;85(7):1059-1067. doi: 10.1253/circj.CJ-20-0938. Epub 2021 Jan 7.
A thorough understanding of the anatomy of the aortic valve is necessary for aortic valve-sparing surgery. Normal valvar dimensions and their relationships in the living heart, however, have yet to be fully investigated in a 3-dimensional fashion.
In total, 123 consecutive patients (66±12 years, Men 63%) who underwent coronary computed tomographic angiography were enrolled. Mid-diastolic morphology of the aortic roots, including height of the interleaflet triangles, geometric height, free margin length of each leaflet, effective height, and coaptation length were measured using multiplanar reconstruction images. Average height of the interleaflet triangle, geometric height, free margin length, effective height, and the coaptation length were 17.3±1.8, 14.7±1.3, 32.6±3.6, 8.6±1.4, and 3.2±0.8 mm, respectively. The right coronary aortic leaflet displayed the longest free margin length and shortest geometric height. Geometric height, free margin length, and effective height showed positive correlations with aortic root dimensions. Coaptation length, however, remained constant regardless of aortic root dimensions.
Diversities, as well as characteristic relationships among each value involving the aortic root, were identified using living-heart datasets. The aortic leaflets demonstrated compensatory elongation along with aortic root dilatation to maintain constant coaptation length. These measurements will serve as the standard value for revealing the underlying mechanism of aortic regurgitation to plan optimal aortic valve-sparing surgery.
深入了解主动脉瓣解剖结构对于主动脉瓣保留手术至关重要。然而,活体心脏中正常瓣叶尺寸及其相互关系尚未以三维方式得到充分研究。
共纳入 123 例连续接受冠状动脉计算机断层血管造影检查的患者(66±12 岁,男性 63%)。使用多平面重建图像测量主动脉根部舒张中期形态,包括瓣叶间三角高度、几何高度、每个瓣叶游离缘长度、有效高度和对合长度。瓣叶间三角平均高度、几何高度、游离缘长度、有效高度和对合长度分别为 17.3±1.8、14.7±1.3、32.6±3.6、8.6±1.4 和 3.2±0.8mm。右冠状动脉瓣叶游离缘长度最长,几何高度最短。几何高度、游离缘长度和有效高度与主动脉根部尺寸呈正相关。然而,对合长度与主动脉根部尺寸无关,保持不变。
使用活体心脏数据集确定了主动脉根部各值之间的差异和特征关系。主动脉瓣叶随着主动脉根部扩张而发生代偿性伸长,以保持恒定的对合长度。这些测量值将作为揭示主动脉瓣反流潜在机制、规划最佳主动脉瓣保留手术的标准值。