Prenzel Freerk, Nissler Karl, Siekmeyer Manuela, Vom Hove Maike, Schleicher Gudrun, Kiess Wieland, Lipek Tobias
Department of Pediatrics, University of Leipzig Medical Center, Leipzig, Germany.
Leipzig Interdisciplinary Center for Allergy (LICA), Leipzig, Germany.
J Asthma Allergy. 2020 Dec 31;13:753-756. doi: 10.2147/JAA.S287315. eCollection 2020.
On our pediatric intensive care unit, we successfully treated a 10-year-old boy with severe pulmonary edema due to anaphylaxis after his last injection of a 3-year course of allergen immunotherapy (AIT). In view of the severity of the adverse event, we initiated a case analysis with all involved medical professionals. The evaluation revealed delayed administration of epinephrine due to dosing uncertainty and underestimation of severity. Consequently, all involved institutions established epinephrine auto-injectors (EAIs) in their emergency equipment. We suggest providing EAIs in every practice conducting AIT, as well as in pediatric emergency rooms and ambulances. We would like to remind readers of the risk of anaphylaxis, even on the last day of AIT.
在我们的儿科重症监护病房，我们成功治疗了一名10岁男孩，他在完成为期3年的变应原免疫疗法（AIT）最后一针注射后，因过敏反应出现严重肺水肿。鉴于该不良事件的严重性，我们与所有相关医疗专业人员展开了病例分析。评估发现，由于剂量不确定和对严重程度估计不足，肾上腺素给药延迟。因此，所有相关机构在其急救设备中配备了肾上腺素自动注射器（EAIs）。我们建议在开展AIT的每个医疗机构以及儿科急诊室和救护车上配备EAIs。我们想提醒读者，即使在AIT的最后一天，也存在过敏反应的风险。
