Lee Young Joo, Shin Junyoung, Jung Jin-Min, Kim Eun Key, Jung Jinhong, Jeong Jae Ho, Gong Gyungyub, Ko BeomSeok
Division of Breast Surgery, Department of Surgery, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
Department of Pathology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
J Breast Cancer. 2020 Dec;23(6):665-671. doi: 10.4048/jbc.2020.23.e38.
Bilateral axillary Paget's disease in men is a rare occurrence with limited reports on its diagnosis, treatment, and prognosis. Here, we report the case of a 55-year-old Korean male, who presented with a palpable mass and eczematous skin lesion on the left axilla. An incisional biopsy and histopathologic examination indicated invasive ductal carcinoma with Paget's disease arising in the accessory breast. Magnetic resonance imaging and positron emission tomography revealed no malignancy in the normal breast and other organs. The patient was subjected to a wide excision, wherein the left axillary lymph node was dissected, followed by the administration of adjuvant chemotherapy and radiation therapy. After 17 months of disease-free survival, the patient was diagnosed with Paget's disease of the contralateral accessory breast. He underwent wide excision surgery along with radiation therapy. To the best of our knowledge, this is the first report of bilateral extramammary Paget's disease in a male.
男性双侧腋窝派杰氏病较为罕见，关于其诊断、治疗及预后的报道有限。在此，我们报告一例55岁韩国男性病例，该患者左侧腋窝出现可触及肿块及湿疹样皮肤病变。切开活检及组织病理学检查显示为副乳腺发生的伴有派杰氏病的浸润性导管癌。磁共振成像和正电子发射断层扫描显示正常乳腺及其他器官无恶性病变。该患者接受了广泛切除手术，术中清扫了左侧腋窝淋巴结，随后进行辅助化疗和放疗。在无病生存17个月后，患者被诊断为对侧副乳腺派杰氏病。他接受了广泛切除手术及放疗。据我们所知，这是首例男性双侧乳腺外派杰氏病的报告。
