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肛周佩吉特病——一例报告及当前诊断与治疗综述

Perianal Paget's Disease-a Case Report and a Review of Current Diagnosis and Management.

作者信息

Godbole Chintamani, Mehta Jyoti, Methil Bijoy, Palep Reshma, Bhuta Prajesh

机构信息

Department of Surgical Gastroenterology, Jaslok Hospital and Research Centre, Mumbai, 400026 India.

Jaslok Hospital and Research Centre, Mumbai, India.

出版信息

Indian J Surg Oncol. 2017 Dec;8(4):619-621. doi: 10.1007/s13193-016-0548-7. Epub 2016 Sep 1.

Abstract

Paget's disease is an intraepithelial adenocarcinoma arising from the apocrine gland component of the skin. Paget's disease is most common in the breast but extra mammary disease is also seen. Perianal Paget's disease is a rare form of extramammary disease with few cases reported in literature. It can be primary-arising from the skin or secondary-cutaneous metastases of anorectal or genitourinary malignancy. We hereby wish to report a case of perianal Paget's disease that presented as an eczematous lesion and was diagnosed incidentally on biopsy. After appropriate staging, the patient underwent wide local excision till negative margins were obtained. The resultant tissue defect was successfully covered by split-thickness skin grafting.

摘要

佩吉特病是一种起源于皮肤顶泌汗腺成分的上皮内腺癌。佩吉特病最常见于乳腺,但也可见于乳腺外疾病。肛周佩吉特病是一种罕见的乳腺外疾病形式,文献报道的病例较少。它可以是原发性的——起源于皮肤,也可以是继发性的——肛门直肠或泌尿生殖系统恶性肿瘤的皮肤转移。我们在此报告一例肛周佩吉特病,表现为湿疹样病变,活检时偶然确诊。经过适当的分期后,患者接受了广泛的局部切除,直至切缘阴性。由此产生的组织缺损通过中厚皮片移植成功覆盖。

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本文引用的文献

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