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霉菌性(感染性)假性动脉瘤:诊断难题 - 病例系列

Mycotic (Infected) Pseudoaneurysm, a Diagnostic Challenge - Case Series.

作者信息

Sharma Praveen K, Garisa Sai Sindhura, Kumaran S Vinod, Varma Sparsh

机构信息

Department of Radiodiagnosis, Saveetha Medical College and Hospital, Chennai, Tamil Nadu, India.

出版信息

J Clin Imaging Sci. 2020 Dec 20;10:86. doi: 10.25259/JCIS_134_2020. eCollection 2020.

Abstract

Mycotic pseudoaneurysm (or infected pseudoaneurysm) is an infectious arteritis, leading to the destruction of the arterial wall with the formation of a blind, saccular outpouching contiguous with the arterial lumen. Delayed management or non-management of mycotic pseudoaneurysms is associated with high morbidity and mortality due to complications such as arterial rupture, hemorrhage, and fulminant sepsis. Earlier diagnosis of mycotic pseudoaneurysm is essential for time management. Multidetector computed tomography (MDCT) is a widely used imaging modality for detecting the mycotic pseudoaneurysm, its characterization, and vascular mapping. MDCT findings of mycotic pseudoaneurysm are blind, saccular outpouching of an artery with irregular arterial wall, perivascular soft-tissue mass, or edema. Uncommon results of MDCT include arterial lumen thrombosis, arterial wall calcification, and perivascular gas. Management of mycotic pseudoaneurysm includes endovascular stenting with graft repair, endovascular embolization, open surgery, medical therapy (intravenous antibiotics), or a combination of these. We report three cases of mycotic pseudoaneurysm affecting aortic isthmus, a segmental branch of the pulmonary artery, and the internal mammary artery. All cases posed a diagnostic challenge, which only on subsequent imaging revealed to be a mycotic pseudoaneurysm.

摘要

真菌性假性动脉瘤(或感染性假性动脉瘤)是一种感染性动脉炎,可导致动脉壁破坏,形成与动脉腔相连的盲端、囊状膨出。由于动脉破裂、出血和暴发性脓毒症等并发症,真菌性假性动脉瘤的延迟治疗或不治疗会导致高发病率和死亡率。早期诊断真菌性假性动脉瘤对于及时治疗至关重要。多排螺旋计算机断层扫描(MDCT)是一种广泛用于检测真菌性假性动脉瘤、对其进行特征描述以及血管成像的影像学检查方法。真菌性假性动脉瘤的MDCT表现为动脉的盲端、囊状膨出,动脉壁不规则,血管周围软组织肿块或水肿。MDCT的罕见表现包括动脉腔血栓形成、动脉壁钙化和血管周围气体。真菌性假性动脉瘤的治疗方法包括血管内支架植入联合移植物修复、血管内栓塞、开放手术、药物治疗(静脉使用抗生素)或这些方法的联合应用。我们报告了3例真菌性假性动脉瘤病例,分别累及主动脉峡部、肺动脉的一个节段分支和胸廓内动脉。所有病例均带来了诊断挑战,仅在后续影像学检查中才发现是真菌性假性动脉瘤。

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