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脓肿与动脉瘤:一例结核性脓肿导致主动脉假性动脉瘤的病例。

Abscess and aneurysm: A case of tuberculous abscess causing an aortic pseudo-aneurysm.

作者信息

Gulati Anjalie, Esses Steven

机构信息

Maimonides Medical Center, Brooklyn, NY, USA.

出版信息

Radiol Case Rep. 2025 Jan 7;20(3):1699-1702. doi: 10.1016/j.radcr.2024.12.003. eCollection 2025 Mar.

DOI:10.1016/j.radcr.2024.12.003
PMID:39868058
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11760789/
Abstract

Thoracic aortic pseudoaneurysms are a rare but serious complication of infectious processes, often resulting from mycotic (infectious) aneurysms, occurring when the vessel wall is compromised by an infection, leading to the formation of a pseudoaneurysm [1]. Mycotic aneurysms typically result from bacteremia or fungemia, with common sources being infective endocarditis or other systemic infections. Tuberculosis, though a common infectious disease worldwide, is an unusual cause of aortic pseudoaneurysm formation. We present the case of a 26-year-old Asian male with a history of positive Quantiferon test, who presented with two weeks of back pain, hemoptysis, cough, night sweats, fever, and chills. CT imaging revealed a pseudoaneurysm at the T11-T12 level, associated with an epidural abscess, prevertebral rim-enhancing collection, and signs of osteomyelitis. The patient underwent endovascular repair of the aortic aneurysm, followed by drainage and biopsy of the epidural abscess and antibiotic therapy for the underlying infection. This case demonstrates the rare occurrence of a mycotic aneurysm caused by tuberculous infection, and the importance of early diagnosis and prompt surgical intervention to prevent catastrophic complications such as rupture, sepsis, or neurological impairment.

摘要

胸主动脉假性动脉瘤是感染性疾病罕见但严重的并发症,通常由真菌性(感染性)动脉瘤引起,当血管壁因感染而受损时就会形成假性动脉瘤[1]。真菌性动脉瘤通常由菌血症或真菌血症引起,常见来源为感染性心内膜炎或其他全身感染。结核病虽然是全球常见的传染病,但却是主动脉假性动脉瘤形成的不寻常原因。我们报告一例26岁亚洲男性病例,该患者结核菌素试验阳性,出现背痛、咯血、咳嗽、盗汗、发热和寒战两周。CT成像显示在T11 - T12水平有一个假性动脉瘤,伴有硬膜外脓肿、椎体前缘环形强化灶及骨髓炎迹象。患者接受了主动脉瘤血管内修复术,随后对硬膜外脓肿进行了引流和活检,并针对潜在感染进行了抗生素治疗。该病例表明结核感染引起真菌性动脉瘤的情况罕见,以及早期诊断和及时手术干预以预防诸如破裂、败血症或神经功能损害等灾难性并发症的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1001/11760789/ea6eeb366082/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1001/11760789/c6cc426509b3/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1001/11760789/4640d672029b/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1001/11760789/719411ea3d89/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1001/11760789/ea6eeb366082/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1001/11760789/c6cc426509b3/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1001/11760789/4640d672029b/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1001/11760789/719411ea3d89/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1001/11760789/ea6eeb366082/gr4.jpg

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本文引用的文献

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Mycotic Thoracic Aortic Aneurysm: Epidemiology, Pathophysiology, Diagnosis, and Management.真菌性胸主动脉瘤:流行病学、病理生理学、诊断与治疗
Cureus. 2022 Nov 2;14(11):e31010. doi: 10.7759/cureus.31010. eCollection 2022 Nov.
2
Mycotic (Infected) Pseudoaneurysm, a Diagnostic Challenge - Case Series.霉菌性(感染性)假性动脉瘤:诊断难题 - 病例系列
J Clin Imaging Sci. 2020 Dec 20;10:86. doi: 10.25259/JCIS_134_2020. eCollection 2020.
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Treatment of mycotic superior mesenteric vein pseudoaneurysm via placement of covered endovascular stent.
经覆膜血管内支架置入治疗真菌性肠系膜上静脉假性动脉瘤。
Diagn Interv Radiol. 2020 Nov;26(6):584-586. doi: 10.5152/dir.2020.19542.
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Aortitis.主动脉炎
Circulation. 2008 Jun 10;117(23):3039-51. doi: 10.1161/CIRCULATIONAHA.107.760686.
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Infectious Aortitis.感染性主动脉炎
Curr Treat Options Cardiovasc Med. 2005 Jun;7(2):89-97. doi: 10.1007/s11936-005-0010-6.