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腮腺造釉细胞瘤样尤因肉瘤：两例报告并文献复习

Adamantinoma-Like Ewing Sarcoma of the Parotid Gland: Report of Two Cases and Review of Literature.

作者信息

Alnuaim Hala, Alzahrani Malak, Ghandurah Samirah, Dababo Mohammad

机构信息

Pathology and Laboratory Medicine, King Abdulaziz Medical City, Riyadh, SAU.

Anatomical Pathology, King Saud University, Riyadh, SAU.

出版信息

Cureus. 2020 Dec 3;12(12):e11870. doi: 10.7759/cureus.11870.

DOI:10.7759/cureus.11870
PMID:33409103
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7781571/
Abstract

Adamantinoma-like Ewing sarcoma (ALES) is a rare variant of Ewing sarcoma. It demonstrates heterogeneous morphologic pattern and complex immunophenotypic profile, with a peculiar combination of epithelial and neuroendocrine differentiation. ALES is rarely reported in the head and neck areas, including the parotid salivary gland. Till now, only 10 cases of ALES have been reported in the salivary glands. Herein, we report two cases of ALES involving the parotid gland, adding some valuable insight to the recently reported cases at this site.

摘要

成釉细胞瘤样尤因肉瘤（ALES）是尤因肉瘤的一种罕见变异型。它表现出异质性的形态学模式和复杂的免疫表型特征，具有上皮和神经内分泌分化的特殊组合。头颈部区域（包括腮腺）很少报道有ALES。到目前为止，唾液腺中仅报道了10例ALES。在此，我们报告2例累及腮腺的ALES，为该部位最近报道的病例增添了一些有价值的见解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2340/7781571/bd13cd69d195/cureus-0012-00000011870-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2340/7781571/a0ea2a16148e/cureus-0012-00000011870-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2340/7781571/bd13cd69d195/cureus-0012-00000011870-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2340/7781571/a0ea2a16148e/cureus-0012-00000011870-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2340/7781571/bd13cd69d195/cureus-0012-00000011870-i02.jpg

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Basaloid squamous cell carcinoma with prominent shadow (ghost) cell differentiation. An unreported neoplasm of the parotid gland.

本文引用的文献

1
Adamantinoma-like Ewing Sarcoma of the Salivary Glands: A Newly Recognized Mimicker of Basaloid Salivary Carcinomas.唾液腺似造釉细胞瘤样尤文肉瘤：一种新认识的基底细胞样唾液腺癌的模拟物。
Am J Surg Pathol. 2019 Feb;43(2):187-194. doi: 10.1097/PAS.0000000000001171.
2
Adamantinoma-like Ewing family tumors of the head and neck: a pitfall in the differential diagnosis of basaloid and myoepithelial carcinomas.头颈部的牙釉质瘤样尤因家族肿瘤：基底样癌和肌上皮癌鉴别诊断中的一个陷阱
Am J Surg Pathol. 2015 Sep;39(9):1267-74. doi: 10.1097/PAS.0000000000000460.
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Adamantinoma-like Ewing sarcoma mimicking basal cell adenocarcinoma of the parotid gland: a case report and review of the literature.
基底样鳞状细胞癌伴显著影细胞分化。一种未报道的腮腺肿瘤。
Rom J Morphol Embryol. 2022 Jan-Mar;63(1):221-228. doi: 10.47162/RJME.63.1.25.
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Adamantinoma-Like Ewing Sarcoma of the Head and Neck: A Case-Series of a Rare and Challenging Diagnosis.头颈部似造釉细胞瘤样尤文肉瘤：一种罕见且具挑战性诊断的病例系列。
Head Neck Pathol. 2022 Sep;16(3):679-694. doi: 10.1007/s12105-022-01412-1. Epub 2022 Jan 13.
酷似腮腺基底细胞腺癌的造釉细胞瘤样尤因肉瘤：一例报告并文献复习
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Desmoplastic small round cell tumor of major salivary glands: report of 1 case and a review of the literature.大涎腺促纤维增生性小圆细胞肿瘤：1例报告并文献复习
Appl Immunohistochem Mol Morphol. 2011 Jan;19(1):70-5. doi: 10.1097/PAI.0b013e3181eec73c.
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Morphologic and immunophenotypic diversity in Ewing family tumors: a study of 66 genetically confirmed cases.尤因家族性肿瘤的形态学和免疫表型多样性：一项对66例基因确诊病例的研究
Am J Surg Pathol. 2005 Aug;29(8):1025-33.
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The expanding clinical spectrum of desmoplastic small round-cell tumor: a report of two cases with molecular confirmation.
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