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脊髓损伤患者的反射性出汗:综述

Reflex sweating in patients with spinal cord injury: a review.

作者信息

Fast A

出版信息

Arch Phys Med Rehabil. 1977 Oct;58(10):435-7.

PMID:334108
Abstract

Sweat glands derive their innervation from the sympathetic nervous system. The spinal sympathetic structures that are located in the intermediolateral areas extend from T1-L2 segments and are under the control of hypothalamic centers. Cord transection abolishes the supraspinal control of sudorimotor function. Since sympathetic innervation does not follow a clear segmental distribution, normal sweating may be preserved at a higher or lower level than skin sensation. Nonthermoregulatory reflex sweating is an indication of unchecked spinal cord facilitation and is precipitated by afferent stimuli from bladder, rectum, and various other sources. It is usually a manifestation of mass reflex or autonomic crisis and occurs particularly in cervical or high thoracic lesions. Transection below T8-T10 is not accompanied by reflex sweating. The phenomenon of thermal relfex sweating is controversial. Although some aspects of nonthermoregulatory reflex sweating are still unclear, proper immediate and continuing preventive management will reduce the incidence of this and other autonomic manifestations. Chemical sympathectomy should be a last resort in case of emergency or when the source of facilitation cannot be ascertained.

摘要

汗腺的神经支配来自交感神经系统。位于中间外侧区域的脊髓交感结构从T1-L2节段延伸,受下丘脑中枢控制。脊髓横断会消除对发汗运动功能的脊髓上控制。由于交感神经支配没有明确的节段性分布,正常出汗可能在高于或低于皮肤感觉的水平得以保留。非体温调节性反射性出汗表明脊髓易化不受控制,由来自膀胱、直肠和各种其他来源的传入刺激诱发。它通常是总体反射或自主神经危象的表现,尤其发生在颈部或高位胸椎病变中。T8-T10以下的横断不会伴有反射性出汗。热反射性出汗现象存在争议。尽管非体温调节性反射出汗的某些方面仍不清楚,但适当的即时和持续预防性处理将降低这种及其他自主神经表现的发生率。在紧急情况下或无法确定易化来源时,化学性交感神经切除术应作为最后的手段。

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