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头颈部游离皮瓣术后加强监护病房与非加强监护病房治疗的比较:一项荟萃分析。

Intensive Care Versus Nonintensive Care Ward for Postoperative Management of Head and Neck Free Flaps: A Meta-Analysis.

机构信息

Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Department of Otorhinolaryngology-Head and Neck Surgery, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

出版信息

Facial Plast Surg Aesthet Med. 2021 Dec;23(6):408-416. doi: 10.1089/fpsam.2020.0400. Epub 2020 Oct 13.

Abstract

Although advances in surgical technique and medical management have drastically improved outcomes of free flap reconstructive surgery in head and neck patients, there is no clear consensus on appropriate level of postoperative care. The literature was searched systematically for all comparative studies of intensive care unit (ICU) and non-ICU admissions for head and neck patients. The primary outcomes were flap failure rate, flap complications, and hospital length of stay (LOS). Secondary outcomes included cost implications, medical complications, and rates of revision surgery, readmission, and mortality. Nine articles (2510 patients) were included. Patients admitted to non-ICU wards were not significantly at increased risk for free flap failure, flap-related complications, or longer LOS. Total medical complications were found to have a pooled relative risk (RR) of 0.57 [95% confidence interval (CI) 0.40 to 0.83], favoring the non-ICU cohort. In particular, the non-ICU cohort was less likely to develop neuropsychiatric complications (RR 0.34 [95% CI 0.24 to 0.48]) and sepsis (RR 0.18 [95% CI 0.05 to 0.68]) with no difference in cardiovascular or pulmonary complications. Patients admitted to non-ICU wards did not experience higher rates of adverse flap-related outcomes and had decreased risk of developing medical complications in the studies included in this meta-analysis.

摘要

尽管手术技术和医疗管理的进步极大地改善了头颈部游离皮瓣重建手术的结果,但对于术后护理的适当水平仍没有明确的共识。本文系统地检索了头颈部患者入住重症监护病房(ICU)和非 ICU 的所有对照研究。主要结局是皮瓣失败率、皮瓣并发症和住院时间(LOS)。次要结局包括成本影响、医疗并发症、以及翻修手术、再入院和死亡率的发生率。纳入了 9 篇文章(2510 例患者)。入住非 ICU 病房的患者游离皮瓣失败、皮瓣相关并发症或 LOS 延长的风险没有显著增加。总医疗并发症的合并相对风险(RR)为 0.57(95%置信区间(CI)为 0.40 至 0.83),非 ICU 组更有利。特别是,非 ICU 组发生神经精神并发症(RR 0.34 [95% CI 0.24 至 0.48])和脓毒症(RR 0.18 [95% CI 0.05 至 0.68])的可能性更小,而心血管或肺部并发症无差异。本 meta 分析纳入的研究中,入住非 ICU 病房的患者并未经历更高的不良皮瓣相关结局发生率,并且发生医疗并发症的风险降低。

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