Stekel A, Olivares M, Cayazzo M, Chadud P, Llaguno S, Pizarro F
Institute of Nutrition and Food Technology, University of Chile, Santiago.
Am J Clin Nutr. 1988 Feb;47(2):265-9. doi: 10.1093/ajcn/47.2.265.
In a longitudinal study from age 3 to 15 mo, 276 term, healthy, spontaneously weaned infants received a full-fat acidified milk fortified with 15 mg of elemental Fe as ferrous sulfate and 100 mg of ascorbic acid/100 g of powder and 278 control infants received milk without additives. At ages 9 and 15 mo significant differences were encountered in all measures of Fe nutriture in favor of the fortified group (p less than 0.001). Anemia (Hg less than 110 g/L) was present in 25.7% of unfortified infants compared with only 2.5% in those fortified at age 15 mo. Saturation of transferrin less than 9% was present in 33.8% and serum ferritin less than 10 micrograms/L in 39.1% of the nonfortified infants. The figures for the fortified group were 7 and 8.5% respectively. The efficiency of the fortified acidified milk in eradicating Fe deficiency in the infants while discouraging use by other family members make this milk a useful targeted product in programs of supplementary food distribution in the underdeveloped world.
在一项针对3至15个月大婴儿的纵向研究中，276名足月、健康、自然断奶的婴儿食用了添加15毫克硫酸亚铁元素铁和100毫克抗坏血酸/100克奶粉的全脂酸化牛奶，278名对照婴儿食用了无添加剂的牛奶。在9个月和15个月大时，强化组在铁营养的所有指标上均出现显著差异（p小于0.001）。15个月大时，未强化组婴儿的贫血（血红蛋白低于110克/升）发生率为25.7%，而强化组仅为2.5%。未强化组婴儿转铁蛋白饱和度低于9%的发生率为33.8%，血清铁蛋白低于10微克/升的发生率为39.1%。强化组的相应数字分别为7%和8.5%。强化酸化牛奶在消除婴儿缺铁方面的有效性，同时又能抑制其他家庭成员饮用，使得这种牛奶成为欠发达国家补充食品分发计划中的一种有用的目标产品。
