Sneige N, Dekmezian R H, Silva E G, Cartwright J, Ayala A G
Department of Pathology, University of Texas M. D. Anderson Hospital and Tumor Institute, Houston 77030.
Am J Clin Pathol. 1988 Feb;89(2):148-53. doi: 10.1093/ajcp/89.2.148.
Periodic structures with equally spaced radial striations identified as Liesegang-like rings were seen in two male patients' hemorrhagic perirenal cysts. The patients, one 48 and the other 60 years old, had acute right-flank pain and anemia; both had nephrectomy. The rings, initially believed to represent parasites (Dioctophyma renale), were from 8 to 500 micron in diameter and had uniform, pink-tan, radially striated double walls. Multiple small rings within a larger ring predominated in one case. Morphologically, the rings differed from D. renale when compared with specimens from animals infected naturally or experimentally with the giant kidney worm. Histochemical and immunoperoxidase tests for iron, calcium, mucopolysaccharides, amyloid, keratin, and hemoglobin had negative results. Energy-dispersive x-ray elemental analysis demonstrated no detectable elements; ultrastructurally, however, the rings displayed a fine fibrillary composition with a concentric and radial pattern. These rings are believed to be an end product of a phenomenon resembling or are, in fact, the Liesegang phenomenon. Because these Liesegang-like structures may be mistaken for parasites on fine-needle aspiration or surgical specimens of hemorrhagic areas, pathologists should be aware of them.
在两名男性患者的出血性肾周囊肿中发现了具有等距放射状条纹的周期性结构，被鉴定为类李塞冈环。这两名患者，一名48岁，另一名60岁，均有急性右侧腰痛和贫血症状；两人都接受了肾切除术。这些环最初被认为是寄生虫（肾膨结线虫），直径为8至500微米，具有均匀的、粉褐色的、有放射状条纹的双层壁。在一个病例中，较大环内有多个小环占主导。形态学上，与自然感染或实验感染巨型肾虫的动物标本相比，这些环与肾膨结线虫不同。对铁、钙、粘多糖、淀粉样蛋白、角蛋白和血红蛋白进行的组织化学和免疫过氧化物酶检测结果均为阴性。能量色散X射线元素分析未检测到可检测元素；然而，在超微结构上，这些环显示出具有同心和放射状图案的精细纤维成分。这些环被认为是一种类似李塞冈现象的现象的最终产物，或者实际上就是李塞冈现象。由于这些类李塞冈结构在出血区域的细针穿刺或手术标本中可能被误认为是寄生虫，病理学家应该对此有所了解。
