Chemical constituents of twigs and their biological activity.

A new megastigmane-type norsesquiterpenoid glycoside, chaemeloside (), was isolated from the twigs of together with 11 known phytochemicals through chromatographic methods. The chemical structure of the new isolate was determined by conventional 1D and 2D NMR data analysis, ECD experiment, hydrolysis followed by a modified Mosher's method, and LC-MS analysis. The characterized compounds' biological effects including cytotoxicity against cancer cell lines, antineuroinflammatory activity, and potential neurotrophic effect were evaluated.