Division of Medical Physics & Department of Radiation Oncology, Rajiv Gandhi Cancer Institute and Research Centre, Sector-5, Rohini, New Delhi, 110085, India.
Amity School of Applied Sciences, Amity University (AUUP), Noida, India.
J Egypt Natl Canc Inst. 2021 Jan 7;33(1):2. doi: 10.1186/s43046-020-00057-x.
The number of people with implanted hip prosthesis has grown worldwide. For radiotherapy planning of patients with hip implants, few main challenges are encountered. The aim of the present study was to evaluate the feasibility of different planning algorithms in the presence of high-density metallic implant in the treatment of patients with carcinoma cervix.
It was found that D were 44.49 ± 0.11, 44.51 ± 0.13, 44.39 ± 0.22, and 44.45 ± 0.16 Gy for 4FMC6MV (4-field technique calculated with Monte-Carlo algorithm and 6 MV photon energy), 4FMC6MV_WP (4-field technique calculated with Monte-Carlo algorithm and 6 MV photon energy without prosthesis), 4FCC6MV (4-field technique calculated with collapse-cone-convolution algorithm and 6 MV photon energy), and 4FCC6MV_WP (4-field technique calculated with collapse-cone-convolution algorithm and 6 MV photon energy without prosthesis) respectively. Similarly, D were 49.40 ± 0.84, 49.05 ± 0.76, 48.97 ± 0.91, and 48.57 ± 0.85 Gray (Gy) for 4FMC6MV, 4FMC6MV_WP, 4FCC6MV, and 4FCC6MV_WP respectively. The present study has not suggested any major difference between the Monte-Carlo (MC) and collapse-cone-convolution (CCC) calculation algorithm in the presence of high-Z metallic implants. Volume of bowel receiving 15 Gy dose has shown a significant difference with prosthesis cases. This study investigates that hip prosthesis creates considerable changes in the treatment planning of cervical malignancies.
CCC algorithm is in good agreement with MC calculation algorithm in the presence of high-density metallic implants in terms of target coverage and avoidance organ sparing except few parameters.
全球范围内植入髋关节假体的人数不断增加。对于髋关节植入物患者的放射治疗计划,存在一些主要挑战。本研究旨在评估在存在高密度金属植入物的情况下,不同规划算法在治疗宫颈癌患者中的可行性。
发现 4FMC6MV(使用蒙特卡罗算法和 6 MV 光子能量计算的 4 野技术)、4FMC6MV_WP(使用蒙特卡罗算法和 6 MV 光子能量计算但无假体的 4 野技术)、4FCC6MV(使用坍缩锥卷积算法和 6 MV 光子能量计算的 4 野技术)和 4FCC6MV_WP(使用坍缩锥卷积算法和 6 MV 光子能量计算但无假体的 4 野技术)的 D 值分别为 44.49±0.11、44.51±0.13、44.39±0.22 和 44.45±0.16Gy。同样,4FMC6MV、4FMC6MV_WP、4FCC6MV 和 4FCC6MV_WP 的 D 值分别为 49.40±0.84、49.05±0.76、48.97±0.91 和 48.57±0.85 Gray(Gy)。本研究未表明在存在高 Z 值金属植入物的情况下,蒙特卡罗(MC)和坍缩锥卷积(CCC)计算算法之间存在任何重大差异。接受 15Gy 剂量的肠体积显示与假体病例存在显著差异。本研究调查了髋关节假体在宫颈癌治疗计划中会产生相当大的变化。
在存在高密度金属植入物的情况下,CCC 算法与 MC 计算算法在靶区覆盖和避免器官保护方面除了少数参数外,具有良好的一致性。