Sienko D G, Bartlett P C, McGee H B, Wentworth B B, Herndon J L, Hall W N
Michigan Department of Public Health, Center for Health Promotion, Lansing 48909.
Arch Intern Med. 1988 Mar;148(3):609-12. doi: 10.1001/archinte.148.3.609.
The prevalence of Q fever infection is probably underestimated. In Michigan, the first two reported human cases of Q fever occurred in 1984. The case-patients lived in adjacent, rural counties and had multiple exposures to goats. We conducted a serosurvey of goat owners and a reference population to compare the prevalence of Q fever antibodies in the two-county area. Goat owners were almost three times more likely to be seropositive with Q fever antibodies than the reference population (43% vs 15%). Among goat owners, individual and household seropositivity prevalences were positively correlated with the number of goats, the number of positive goats, and the number of goat births on the farm. Q fever should be considered more often in the differential diagnosis of patients with compatible illness, especially those with frequent animal contact.
Q热感染的患病率可能被低估了。在密歇根州，1984年报告了首例两例人类Q热病例。病例患者居住在相邻的农村县，多次接触山羊。我们对山羊养殖户和参照人群进行了血清学调查，以比较两县地区Q热抗体的患病率。山羊养殖户血清学检测Q热抗体呈阳性的可能性几乎是参照人群的三倍（43%对15%）。在山羊养殖户中，个体和家庭血清学阳性患病率与农场山羊数量、阳性山羊数量以及山羊产仔数量呈正相关。对于患有相应疾病的患者，尤其是那些经常接触动物的患者，在鉴别诊断时应更常考虑Q热。
