Agrawal Garima, Samal Sangram K
Department of Polymer and Process Engineering, Indian Institute of Technology Roorkee, Saharanpur Campus, Paper Mill Road, Saharanpur 247 001, Uttar Pradesh, India.
Materials Research Centre, Indian Institute of Science, Bangalore 560 012, India.
ACS Biomater Sci Eng. 2018 Apr 9;4(4):1285-1299. doi: 10.1021/acsbiomaterials.8b00258. Epub 2018 Mar 16.
In recent years, polymeric biomaterials have emerged as a potential candidate for therapeutic applications owing to their salient features. The characterization of these drugs and bioactive molecules loaded polymer based biomaterials is an important prerequisite for obtaining a deep understanding of their physicochemical behavior in order to ensure their successful clinical use. There are a variety of complementary characterization techniques available for the characterization of the biomaterials. This review highlights the potential of Raman spectroscopy including its importance for investigating the molecular structure of polymeric materials along with a brief description of its principles, instrumentation, and recent advances.
近年来,聚合物生物材料因其显著特性已成为治疗应用的潜在候选材料。对这些负载药物和生物活性分子的聚合物基生物材料进行表征,是深入了解其物理化学行为以确保其临床成功应用的重要前提。有多种互补的表征技术可用于生物材料的表征。本综述强调了拉曼光谱的潜力,包括其在研究聚合物材料分子结构方面的重要性,并简要描述了其原理、仪器设备和最新进展。