College of Chemistry, Chemical Engineering and Materials Science, Collaborative Innovation Center for New Type Urbanization and Social Governance of Jiangsu Province, Soochow University, Suzhou, 215123, P. R. China.
Macromol Rapid Commun. 2020 Apr;41(8):e1900430. doi: 10.1002/marc.201900430. Epub 2020 Mar 5.
This review focuses on the attachment of polymer brushes to polymeric biomaterial substrates by chemical surface modification methods for biomedical applications. In the first part of this paper, a general introduction to the synthesis of polymer brushes is given. Thereafter, a comprehensive overview of recent work on the chemical surface modification of polymeric biomaterials, with a focus on "grafting-to," "grafting-from," and "grafting-through" strategies, is provided. Finally, some representative cutting-edge biomedical applications of modified polymeric biomaterials, mainly including antifouling materials and biocompatible materials, are highlighted. On the basis of this literature study, a perspective on future trends in this field is provided.
这篇综述主要关注通过化学表面改性方法将聚合物刷附着到聚合物生物材料基底上，以应用于生物医学领域。本文的第一部分对聚合物刷的合成进行了一般性介绍。此后，对聚合物生物材料的化学表面改性的最新工作进行了全面概述，重点介绍了“接枝到”、“接枝自”和“接枝通过”策略。最后，强调了改性聚合物生物材料的一些有代表性的前沿生物医学应用，主要包括抗污材料和生物相容材料。基于这项文献研究，提供了对该领域未来趋势的展望。
