University of Niš, Faculty of Medicine, RS-18000 Niš, Serbia.
University of Niš, Faculty of Medicine, RS-18000 Niš, Serbia.
Mater Sci Eng C Mater Biol Appl. 2017 Oct 1;79:930-949. doi: 10.1016/j.msec.2017.05.127. Epub 2017 May 18.
A review of recent advances in instrumental methods and techniques for structural and physicochemical characterization of biomaterials and bone tissue is presented in this paper. In recent years, biomaterials attracted great attention primarily because of the wide range of biomedical applications. This paper focuses on the practical aspects of instrumental methods and techniques that were most often applied (X-ray methods, vibrational spectroscopy (IR and Raman), magnetic-resonance spectroscopy (NMR and ESR), mass spectrometry (MS), atomic absorption spectrometry (AAS) and inductively coupled plasma-atomic emission spectrometry (ICP-AES), thermogravimetry (TG), differential thermal analysis (DTA) and differential scanning calorimetry (DSC), scanning electron microscopy (SEM), transmission electron microscopy (TEM)) in the structural investigation and physicochemical characterization of biomaterials and bone tissue. The application of some other physicochemical methods was also discussed. Hands-on information is provided about these valuable research tools, emphasizing practical aspects such as typical measurement conditions, their limitations and advantages, interpretation of results and practical applications.
本文综述了近年来用于生物材料和骨组织结构和物理化学特性表征的仪器方法和技术的最新进展。近年来，生物材料受到了广泛关注，主要是因为它们在生物医学中的广泛应用。本文重点介绍了在生物材料和骨组织的结构研究和物理化学特性表征中最常应用的仪器方法和技术的实际方面（X 射线方法、振动光谱（IR 和拉曼）、磁共振光谱（NMR 和 ESR）、质谱（MS）、原子吸收光谱（AAS）和电感耦合等离子体原子发射光谱（ICP-AES）、热重分析（TG）、差示热分析（DTA）和差示扫描量热法（DSC）、扫描电子显微镜（SEM）、透射电子显微镜（TEM））。还讨论了其他一些物理化学方法的应用。本文提供了有关这些有价值的研究工具的实践信息，强调了典型测量条件、它们的优缺点、结果解释和实际应用等实际方面。
