Chatterjee Bandhan, Ghoshal Archita, Chattopadhyay Arun, Ghosh Siddhartha Sankar
ACS Biomater Sci Eng. 2018 Mar 12;4(3):1005-1012. doi: 10.1021/acsbiomaterials.7b00980. Epub 2018 Feb 2.
dGTP-templated facile synthesis of luminescent gold nanoclusters (Au NCs) in the presence of cisplatin following PEG coating developed spherical composite NPs. The composite NPs delivered cisplatin efficiently into HeLa cells to induce apoptosis-mediated cell death, and simultaneously bioimaged the cellular uptake.
在聚乙二醇（PEG）包覆后，在顺铂存在的情况下，通过dGTP模板法轻松合成发光金纳米团簇（Au NCs），制备出球形复合纳米颗粒（NPs）。这些复合纳米颗粒将顺铂高效递送至HeLa细胞中，诱导凋亡介导的细胞死亡，同时对细胞摄取进行生物成像。
