脑小血管病。
Cerebral Small Vessel Disease.
机构信息
Department of Neurosurgery and Pediatric Neurosurgery, Medical University of Lublin, 20-954 Lublin, Poland.
Department of Immunology, Medical University of Lublin, 20-093 Lublin, Poland.
出版信息
Int J Mol Sci. 2020 Dec 20;21(24):9729. doi: 10.3390/ijms21249729.
Abstract
Cerebral small vessel disease (CSVD) represents a cluster of various vascular disorders with different pathological backgrounds. The advanced vasculature net of cerebral vessels, including small arteries, capillaries, arterioles and venules, is usually affected. Processes of oxidation underlie the pathology of CSVD, promoting the degenerative status of the epithelial layer. There are several classifications of cerebral small vessel diseases; some of them include diseases such as Binswanger's disease, leukoaraiosis, cerebral microbleeds (CMBs) and lacunar strokes. This paper presents the characteristics of CSVD and the impact of the current knowledge of this topic on the diagnosis and treatment of patients.
摘要
脑小血管病（CSVD）代表了一系列不同病理背景的血管病变。大脑血管的高级血管网络，包括小动脉、毛细血管、微动脉和微静脉，通常会受到影响。氧化过程是 CSVD 病理的基础，促进了上皮层的退行性状态。脑小血管病有几种分类；其中一些包括宾斯旺格病、脑白质病变、脑微出血（CMBs）和腔隙性脑梗死等疾病。本文介绍了 CSVD 的特征，以及目前对这一课题的认识对患者诊断和治疗的影响。
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