Lee Juyoun, Sohn Eun Hee, Oh Eungseok, Lee Ae Young
Department of Neurology, Chungnam National University Hospital, Chungnam National University School of Medicine, Daejeon, Korea.
Dement Neurocogn Disord. 2018 Sep;17(3):73-82. doi: 10.12779/dnd.2018.17.3.73. Epub 2018 Dec 6.
Cerebral microbleeds (CMBs) are increasingly recognized neuroimaging findings, occurring with cerebrovascular disease, dementia, and aging. CMBs are associated with subsequent hemorrhagic and ischemic stroke, and also with an increased risk of cognitive deterioration and dementia. They occur in the setting of impaired small vessel integrity due to hypertension or cerebral amyloid angiopathy. This review summarizes the concepts, cause or risk factors, histopathological mechanisms, and clinical consequences of CMBs.
脑微出血（CMBs）是越来越被认可的神经影像学表现，见于脑血管疾病、痴呆和衰老过程中。CMBs与随后发生的出血性和缺血性卒中相关，也与认知功能恶化和痴呆风险增加有关。它们发生于因高血压或脑淀粉样血管病导致的小血管完整性受损的情况下。本综述总结了CMBs的概念、病因或危险因素、组织病理学机制及临床后果。
