Melamed Naomi, Iddawela Sashini, Poole Grace Olivia Jane, Ajibade Ayomikun, Harky Amer
St George's Medical School, University of London, London, UK.
Department of Respiratory Medicine, University Hospitals Birmingham, Birmingham, UK.
Cardiol Young. 2021 Jan;31(1):31-37. doi: 10.1017/S1047951120004849. Epub 2021 Jan 11.
Extra-corporeal membrane oxygenation is a life-saving modality to support the cardiac and/or pulmonary system as a form of life support in resuscitation, post-cardiotomy, as a bridge to cardiac transplantation and in respiratory failure. Its use in the paediatric and neonatal population has proven incredibly useful. However, extra-corporeal membrane oxygenation is also associated with a greater rate of mortality and complications, particularly in those with co-morbidities. As a result, interventions such as ventricular assist devices have been trialled in these patients. In this review, we provide a comprehensive analysis of the current literature on extra-corporeal membrane oxygenation for cardiac support in the paediatric and neonatal population. We evaluate its effectiveness in comparison to other forms of mechanical circulatory support and focus on areas for future development.
体外膜肺氧合是一种挽救生命的方式,用于支持心脏和/或肺部系统,作为复苏、心脏手术后、作为心脏移植桥梁以及呼吸衰竭时的一种生命支持形式。它在儿科和新生儿人群中的应用已被证明非常有用。然而,体外膜肺氧合也与更高的死亡率和并发症发生率相关,尤其是在患有合并症的患者中。因此,已经在这些患者中试验了诸如心室辅助装置等干预措施。在本综述中,我们对目前关于儿科和新生儿人群心脏支持体外膜肺氧合的文献进行了全面分析。我们将其与其他形式的机械循环支持进行有效性评估,并关注未来的发展领域。