HSIL 和 ASC-H 细胞学、阴道镜和组织病理学的相关性。

Cytological, Colposcopic and Pathohistological Correlation of HSIL and ASC H Findings.

机构信息

Gynecology Centre ,,Dr Mahira Jahić" Tuzla, Bosnia and Herzegovina.

Faculty of Medicine, University of Tuzla, Tuzla, Bosnia and Herzegovina.

出版信息

Med Arch. 2020 Oct;74(5):381-383. doi: 10.5455/medarh.2020.74.381-383.

DOI:10.5455/medarh.2020.74.381-383

PMID:33424094

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7780795/

Abstract

INTRODUCTION

Cervical cancer can be successfully prevented by timely detection of changes that precede it such as atypical (ASC-H) and high grade squamous lesions (HSIL).

AIM

To investigate the correlation between Pap smear and colposcopy in the detection of premalignant and malignant cervical lesions based on a pathohistological finding.

METHODS

In a retrospective study 118 patients with HSIL and ASC-H findings were examined. A Pap smear, colposcopic examination and cervical canal biopsy were performed. The study was conducted at the Gynecological Center "Dr Mahira Jahic" Tuzla and the Clinical Center Tuzla, Department of Gynecology and Obstetrics.

RESULTS

1049 abnormal Pap tests were analyzed, ASCUS in 51,8% (N-544), LSIL 32,1% (N-337), HSIL 7,7% (N-81) and ASC-H 3,5% (N-37), AGC 4,8% (N-51). The mean age of the subjects with the abnormal Pap test was 46.33 ± 3.2. The age of patients with ASCUS lesion was 38,6 , LSIL 41,0, ASC-H was 47,3 , HSIL (CIN II and CIN III) 45,8 , while patients with CIS were 51,2 years. Pathological histology HSIL confirmed a high grade lesion in 67,7% (CIN II, CIN III and CIS) (N-55), in 32% (N-26) a lower grade CIN I in 18,5% and chronic cervicitis in 13,5% (N-11). In ASC-H lesion pathohistological HSIL was found in 13,5% (N-5), CIN I 13,5% (N-5) and chronic cervicitis 48,6 % (N-18). Abnormal colposcopic imaging with HSIL lesion was found in 72,9% (N-69), in 8,6% (N-7) was unsatisfactory and in 18,5% (N-15) the colposcopic finding was normal. In ASC-H lesions, abnormal colposcopic imaging was found in 40,5% (N-15), unsatisfactory findings in 10,8% (N-4), and normal findings in 48,6% (N-18).

CONCLUSION

Colposcopy has proven to be better method than cytology with an accuracy of 72,9% in high-grade lesion such as HSIL and ASC-H.

摘要

简介

通过及时检测宫颈癌前病变，如非典型（ASC-H）和高级别鳞状上皮内病变（HSIL），可以成功预防宫颈癌。

目的

基于组织病理学发现，研究巴氏涂片和阴道镜检查在检测癌前和恶性宫颈病变中的相关性。

方法

在一项回顾性研究中，对 118 例 HSIL 和 ASC-H 发现的患者进行了检查。进行了巴氏涂片、阴道镜检查和宫颈管活检。该研究在图兹拉的“马赫拉·贾希奇博士”妇科中心和图兹拉临床中心妇产科进行。

结果

分析了 1049 例异常巴氏涂片检查，其中 ASCUS 占 51.8%（N-544），LSIL 占 32.1%（N-337），HSIL 占 7.7%（N-81），ASC-H 占 3.5%（N-37），AGC 占 4.8%（N-51）。异常巴氏涂片检查患者的平均年龄为 46.33±3.2 岁。ASCUS 病变患者的年龄为 38.6 岁，LSIL 为 41.0 岁，ASC-H 为 47.3 岁，HSIL（CIN II 和 CIN III）为 45.8 岁，而 CIS 患者为 51.2 岁。组织病理学 HSIL 证实高级别病变在 67.7%（CIN II、CIN III 和 CIS）（N-55）中，在 32%（N-26）中为低级别 CIN I，在 18.5%（N-11）中为慢性宫颈炎，在 13.5%（N-11）中为慢性宫颈炎。在 ASC-H 病变中，组织病理学 HSIL 为 13.5%（N-5），CIN I 为 13.5%（N-5），慢性宫颈炎为 48.6%（N-18）。HSIL 病变的阴道镜检查异常发现为 72.9%（N-69），不满意的发现为 8.6%（N-7），正常发现为 18.5%（N-15）。在 ASC-H 病变中，阴道镜检查异常发现为 40.5%（N-15），不满意发现为 10.8%（N-4），正常发现为 48.6%（N-18）。