Michelangeli F, Ruiz M C, Dominguez M G, Parthe V
Instituto Venezolano de Investigaciones Científicas-IVIC, Caracas, Venezuela.
Cell Tissue Res. 1988 Jan;251(1):225-7. doi: 10.1007/BF00215469.
Gastric glands of submammalian vertebrates are formed by one single cell type known as the oxyntopeptic cell. This cell secretes both hydrochloric acid and pepsinogen. In mammals, this cell differentiates into an acid secreting cell and a pepsinogen secreting one. In the elasmobranch fish Hexanchus griseus we observed, by means of histological studies at the light- and electron-microscopic levels, two different cell types for the secretion of acid and zymogen. This organization represents an evolutionary divergence in a primitive animal, i.e., the appearance of a feature that is acquired much later in evolution, in mammals.
